NRG4

Gene Symbol NRG4
Entrez Gene 145957
Alt Symbol HRG4
Species Human
Gene Type protein-coding
Description neuregulin 4
Other Description heregulin 4|pro-NRG4|pro-neuregulin-4, membrane-bound isoform
Swissprots Q8WWG1 A6NIE8
Accessions EAW99227 EAW99228 Q8WWG1 AK307362 AK311204 AK311507 AM392364 CAL35829 AM392365 CAL35830 AM392366 CAL35831 BC017568 AAH17568 BX538100 CAD98015 CR749519 CAH18333 HQ448724 ADQ33202 NM_138573 NP_612640
Function Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity). {ECO:0000250}.
Subcellular Location Pro-neuregulin-4, membrane-bound isoform: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Does not seem to be active. {ECO:0000250}.
Top Pathways ErbB signaling pathway

Neuregulin-4 CRISPR/Cas9 KO Plasmid (h) - sc-417888 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 HDR Plasmid (h) - sc-417888-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 Double Nickase Plasmid (h) - sc-417888-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 Double Nickase Plasmid (h2) - sc-417888-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 CRISPR Activation Plasmid (h) - sc-417888-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 CRISPR Activation Plasmid (h2) - sc-417888-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 Lentiviral Activation Particles (h) - sc-417888-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 Lentiviral Activation Particles (h2) - sc-417888-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neuregulin-4 siRNA (h) - sc-106298 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neuregulin-4 shRNA Plasmid (h) - sc-106298-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neuregulin-4 shRNA (h) Lentiviral Particles - sc-106298-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU075461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15511 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15511 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

NRG4 siRNA (Human) - CRJ5453 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NRG4 (NM_138573.3) - SHH355068 from Creative biogene

Category siRNA
Species Reactivities Human

Human NRG4 siRNA - orb275954 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NRG4 shRNA Plasmid (Human) - CHJ5453 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NRG4 miRNA 3'UTR clone - MiUTR4H-TG06128 from Creative biogene

Species Reactivities Human
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