SOCS6

Gene Symbol	SOCS6
Entrez Gene	9306
Alt Symbol	CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
Species	Human
Gene Type	protein-coding
Description	suppressor of cytokine signaling 6
Other Description	STAT induced STAT inhibitor-4|cytokine-inducible SH2 protein 4|suppressor of cytokine signaling 4
Swissprots	Q8WUM3 O14544
Accessions	EAW66522 EAW66523 EAW66524 O14544 AB006968 BAA22538 AF161545 AAF29032 AK024356 BC020082 AAH20082 XM_005266783 XP_005266840 NM_004232 NP_004223
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor. {ECO:0000250, ECO:0000269|PubMed:21030588}.
Top Pathways	Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SOCS6 full length protein - ab152969 from Abcam Category Protein Source Wheat germ Species Human

SOCS6 / SOCS-6 Antibody Blocking Peptide - LS-E2987 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SOCS-4 Protein - H00122809-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SOCS-6 Protein - H00009306-P01 from Novus Biologicals Category Protein Prices $250.00, $529.00 Sizes 2 µg, 25 µg Source Wheat Germ Species Human

SOCS6-Antibody-N-term-Blocking-peptide - BP14118a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOCS4 blocking peptide - GTX89892-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Pig, Bovine

SOCS6 / CIS4 - H00009306-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SOCS6 / CIS4 - H00009306-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SOCS6 fusion protein - Ag3096 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SOCS6, GST-tagged - SOCS6-2873H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Suppressor of cytokine signaling 6(SOCS6) - CSB-YP022395HU CSB-EP022395HU CSB-BP022395HU CSB-MP022395HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SOCS6 / CIS4 (full length, N-term HIS tag) - TP760068 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SOCS4 Peptide, Human - M34GP14877H from Creative Peptides Category Peptide Source Synthetic. Species Human

SOCS6 Peptide, Human - M34GP14879H from Creative Peptides Category Peptide Source Synthetic. Species Human

SOCS4 Immunizing peptide - orb17635 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Suppressor of cytokine signaling 4 (SOCS4), Recombinant Protein - MBS1388866 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,440.00, $1,440.00, $1,975.00, $1,975.00, $2,440.00, $2,440.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Suppressor of cytokine signaling 6 (SOCS6), Recombinant Protein - MBS1208876 from MyBioSource Category Protein Prices $1,325.00, $1,325.00, $1,545.00, $1,545.00, $2,195.00, $2,195.00, $2,660.00, $2,660.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SOCS6 fusion protein - Ag25594 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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