SOCS6

Gene Symbol SOCS6
Entrez Gene 9306
Alt Symbol CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
Species Human
Gene Type protein-coding
Description suppressor of cytokine signaling 6
Other Description STAT induced STAT inhibitor-4|cytokine-inducible SH2 protein 4|suppressor of cytokine signaling 4
Swissprots Q8WUM3 O14544
Accessions EAW66522 EAW66523 EAW66524 O14544 AB006968 BAA22538 AF161545 AAF29032 AK024356 BC020082 AAH20082 XM_005266783 XP_005266840 NM_004232 NP_004223
Function SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor. {ECO:0000250, ECO:0000269|PubMed:21030588}.
Top Pathways Prolactin signaling pathway

SOCS-6 CRISPR/Cas9 KO Plasmid (h) - sc-402344 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 HDR Plasmid (h) - sc-402344-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 Double Nickase Plasmid (h) - sc-402344-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 Double Nickase Plasmid (h2) - sc-402344-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 CRISPR Activation Plasmid (h) - sc-402344-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 CRISPR Activation Plasmid (h2) - sc-402344-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 Lentiviral Activation Particles (h) - sc-402344-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 Lentiviral Activation Particles (h2) - sc-402344-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SOCS-6 siRNA (h) - sc-36520 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SOCS-6 shRNA Plasmid (h) - sc-36520-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SOCS-6 shRNA (h) Lentiviral Particles - sc-36520-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SOCS-4 RNAi - H00122809-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SOCS-4 RNAi - H00122809-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU105671 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20325 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20325 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SOCS6 siRNA (Human) - CRH6155 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SOCS-6 RNAi - H00009306-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SOCS6 - MBS8233342 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SOCS6 (NM_004232.3) - SHH414996 from Creative biogene

Category siRNA
Species Reactivities Human

SOCS6 shRNA Plasmid (Human) - CHH6155 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SOCS6 miRNA 3'UTR clone - MiUTR1H-09735 from Creative biogene

Species Reactivities Human
Search more