CMBL

Gene Symbol CMBL
Entrez Gene 134147
Alt Symbol JS-1
Species Human
Gene Type protein-coding
Description carboxymethylenebutenolidase homolog (Pseudomonas)
Other Description carboxymethylenebutenolidase homolog|carboxymethylenebutenolidase-like (Pseudomonas)
Swissprots Q96DG6 Q8TED6 D3DTC7
Accessions EAX08070 EAX08071 Q96DG6 AJ278125 CAC81950 AK074197 BAB85014 AK315390 BAG37783 BC001573 AAH01573 BX647141 DA628493 HQ447384 ADQ31870 NM_138809 NP_620164
Function Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin. {ECO:0000269|PubMed:20177059}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:20177059}.
Tissue Specificity Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level). {ECO:0000269|PubMed:20177059}.

CMBL (B-5) - sc-514233 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CMBL (B-5): sc-514233. Western blot analysis of CMBL expression in non-transfected: sc-117752 (A) and human CMBL transfected: sc-113552 (B) 293T whole cell lysates.

CMBL (C-5) - sc-374248 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CMBL (C-5): sc-374248. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

CMBL (F-3) - sc-514234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CMBL (F-3): sc-514234. Western blot analysis of CMBL expression in non-transfected: sc-117752 (A) and human CMBL transfected: sc-113552 (B) 293T whole cell lysates.

CMBL (D-14) - sc-167500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CMBL (D-14): sc-167500. Western blot analysis of CMBL expression in non-transfected: sc-117752 (A) and human CMBL transfected: sc-113552 (B) 293T whole cell lysates.

CMBL (FL-245) - sc-134616 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CMBL (FL-245): sc-134616. Western blot analysis of CMBL expression in Hep G2 whole cell lysate.

CMBL (G-15) - sc-167501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CMBL (G-15): sc-167501. Western blot analysis of CMBL expression in non-transfected: sc-117752 (A) and human CMBL transfected: sc-113552 (B) 293T whole cell lysates.

Anti-LOC134147 antibody - ab67426 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-LOC134147 antibody (ab67426) at 1/500 dilutionLane 1 : LOC134147 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-CMBL Antibody - LS-C307001 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CMBL Antibody (clone AT2B11) - LS-C175818 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2B11
Western Blot: The extracts of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500-1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

CMBL Antibody - NBP1-82069 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CMBL Antibody (2B11) - NBP2-22618 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B11
Western Blot: CMBL Antibody (2B11) [NBP2-22618] - The extracts of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

CMBL Antibody - H00134147-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CMBL Antibody [H00134147-B01] - analysis of LOC134147 expression in transfected 293T cell line by LOC134147 MaxPab polyclonal antibody (B01). Lane 1: LOC134147 transfected lysate (28.00 KDa). Lane 2: Non-transfected lysate.

CMBL Antibody - H00134147-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CMBL Antibody [H00134147-B01P] - analysis of LOC134147 expression in transfected 293T cell line by LOC134147 MaxPab polyclonal antibody. Lane 1: LOC134147 transfected lysate (26.95 KDa). Lane 2: Non-transfected lysate.

Anti-CMBL antibody produced in rabbit - HPA036571 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CMBL: <B>Cat. No. HPA036571</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Anti-CMBL (159-170) antibody produced in rabbit - SAB1103460 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human CMBL was separated on SDS-PAGE, blotted with Anti-CMBL (159-170) (<B>Cat. No.SAB1103460</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + CMBL immunizing peptide (human, 159-170)

Anti-CMBL (206-220) antibody produced in rabbit - SAB1103461 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human CMBL was separated on SDS-PAGE, blotted with Anti-CMBL (206-220) (<B>Cat. No.SAB1103461</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + CMBL immunizing peptide (human, 206-220)

Anti-CMBL antibody produced in mouse - SAB1408326 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CMBL: <B>Cat. No. SAB1408326</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~27 kDa using CMBL transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

CMBL antibody [AT2B11] - GTX53701 from GeneTex

Prices $319.00
Sizes 100 μl
Host Mouse
Clonality Monoclonal
Clone AT2B11
Anti-CMBL antibody [AT2B11] used in Western blot. GTX53701

CMBL antibody [N2C3] - GTX121486 from GeneTex

Host Rabbit
Clonality Polyclonal
Anti-CMBL antibody [N2C3] used in WB-Ag. GTX121486

CMBL antibody - 10R-8393 from Fitzgerald

Prices $175.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT2B11

Anti -CMBL (Carboxymethylenebutenolidase Homolog, FLJ23617) - 125107 from USBiological Life Science

Host Mouse
Clonality Polyclonal

CMBL antibody - 70R-16466 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

CMBL antibody - 17409-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HeLa cells were subjected to SDS PAGE followed by western blot with 17409-1-AP(CMBL antibody) at dilution of 1:200

CMBL antibody - AM50020PU-N from Acris Antibodies

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2B11
The extracts of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection syste

CMBL antibody - AM50020PU-S from Acris Antibodies

Prices $255.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT2B11
The extracts of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection syste
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