STK36

Gene Symbol STK36
Entrez Gene 27148
Alt Symbol FU
Species Human
Gene Type protein-coding
Description serine/threonine kinase 36
Other Description fused homolog|serine/threonine-protein kinase 36
Swissprots Q9ULE2 Q9UF35 B7WPM3 Q8TC32 Q9NRP7 Q9H9N9
Accessions CAC16640 EAW70647 EAW70648 EAW70649 EAW70650 Q9NRP7 AA524236 AA992176 AB033104 BAA86592 AF200815 AAF97028 AK022692 BAB14184 AL133630 CAB63754 BC026158 AAH26158 DB062910 DQ891739 ABM82665 DQ894916 ABM85842 XM_005246464 XP_005246521 XM_011510959 XP_011509261 XM_011510960 XP_011509262 XM_011510961 XP_011509263 XR_922904 NM_001243313 NP_001230242 NM_015690 NP_056505
Function Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. {ECO:0000269|PubMed:10806483}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10806483}. Nucleus {ECO:0000269|PubMed:10806483}. Note=Low levels also present in the nucleus.
Tissue Specificity Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis, where it is localized in germ cells. {ECO:0000269|PubMed:10806483}.
Top Pathways Hedgehog signaling pathway, Basal cell carcinoma

STK36 (P-14) - sc-169454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-STK36 antibody - ab103807 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-STK36 antibody (ab103807) at 5 µg/ml + Mouse testis tissue lysate at 50 µg

Anti-STK36 antibody - ab68975 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-STK36 antibody (ab68975) at 1/500 dilutionLane 1 : STK36 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-STK36 antibody - ab138292 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-STK36 antibody (ab138292) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-STK36 antibody - N-terminal - ab153906 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-STK36 antibody - N-terminal (ab153906) at 1/500 dilution + IMR32 whole cell lysate at 30 µg

Anti-STK36 Antibody (aa387-436) IHC-plus™ - LS-B8588 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STK36 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8588 dilution 5 ug/ml.

Anti-STK36 Antibody - LS-C101312 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-STK36 Antibody (aa373-422) - LS-C200732 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using STK36 antibody.

STK36 Antibody - H00027148-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: STK36 Antibody [H00027148-D01P] - Analysis of STK36 expression in mouse testis.

STK36 Antibody - NBP1-83412 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: STK36 Antibody [NBP1-83412] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

STK36 Antibody - NBP1-83411 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STK36 Antibody - NBP2-20517 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: STK36 Antibody [NBP2-20517] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 5% SDS PAGE gel, diluted at 1:500.

STK36 Antibody - H00027148-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: STK36 Antibody [H00027148-B01P] - Analysis of STK36 expression in transfected 293T cell line by STK36 polyclonal antibody.  Lane 1: STK36 transfected lysate(144.65 KDa). Lane 2: Non-transfected lysate.

STK36 Antibody - NBP1-83410 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STK36 Antibody - NBP1-52135 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

STK36 Polyclonal Antibody - bs-5724R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STK36 antibody produced in rabbit - HPA030058 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STK36: <B>Cat. No. HPA030058</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.

Anti-STK36 antibody produced in rabbit - SAB4501202 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STK36: <B>Cat. No. SAB4501202</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-STK36 antibody. Cells on the left were treated with the Anti-STK36 antibody. Cells on the right (negative control) were treated with both Anti-STK36 antibody and the synthesized immunogen peptide.

Anti-STK36 antibody produced in rabbit - HPA027453 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STK36: <B>Cat. No. HPA027453</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous duct and leydig cells.

Anti-STK36 antibody produced in rabbit - SAB1401639 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-STK36, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401639</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~144 kDa using Jurkat lysate.

Anti-STK36 antibody produced in rabbit - HPA027409 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-STK36: <B>Cat. No. HPA027409</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in both trophoblastic cells and decidual cells.

STK36-Antibody-C-Term - AF2952a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

STK36 Antibody (OAAF04241) - OAAF04241 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

STK36 Antibody (OAAF07178) - OAAF07178 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

STK36 antibody - orb127252 from Biorbyt

Prices $85.00, $255.00, $425.00
Sizes 25 μg (Trial Size), 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from K562 cells using STK36 antibody
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