STK36

Gene Symbol	STK36
Entrez Gene	27148
Alt Symbol	FU
Species	Human
Gene Type	protein-coding
Description	serine/threonine kinase 36
Other Description	fused homolog|serine/threonine-protein kinase 36
Swissprots	Q9ULE2 Q9UF35 B7WPM3 Q8TC32 Q9NRP7 Q9H9N9
Accessions	CAC16640 EAW70647 EAW70648 EAW70649 EAW70650 Q9NRP7 AA524236 AA992176 AB033104 BAA86592 AF200815 AAF97028 AK022692 BAB14184 AL133630 CAB63754 BC026158 AAH26158 DB062910 DQ891739 ABM82665 DQ894916 ABM85842 XM_005246464 XP_005246521 XM_011510959 XP_011509261 XM_011510960 XP_011509262 XM_011510961 XP_011509263 XR_922904 NM_001243313 NP_001230242 NM_015690 NP_056505
Function	Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. {ECO:0000269|PubMed:10806483}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10806483}. Nucleus {ECO:0000269|PubMed:10806483}. Note=Low levels also present in the nucleus.
Tissue Specificity	Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis, where it is localized in germ cells. {ECO:0000269|PubMed:10806483}.
Top Pathways	Hedgehog signaling pathway, Basal cell carcinoma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human STK36 protein fragment - ab139615 from Abcam Category Protein Prices $302.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human STK36 protein fragment - ab162096 from Abcam Category Protein Source Wheat germ Species Human

STK36 Antibody Blocking Peptide - LS-E27055 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human STK36 Protein - H00027148-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

STK36-Antibody-C-term-Blocking-peptide - BP11543b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

STK36-Antibody-N-term-Blocking-peptide - BP11857a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

STK36 blocking peptide - GTX88419-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

STK36 Peptide - AC21-1877-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

STK36 - H00027148-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

STK36 - H00027148-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

STK36 Peptide - 46-999P from ProSci Category Peptide

STK36 fusion protein - ag3279 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human STK36, GST-tagged - STK36-264H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

Recombinant Human Serine/threonine-protein kinase 36(STK36) ,partial - CSB-YP868303HU CSB-EP868303HU CSB-BP868303HU CSB-MP868303HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

STK36, Peptide - MBS426842 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog

STK36 Recombinant Protein Antigen - NBP1-83412PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

STK36 Recombinant Protein Antigen - NBP1-83411PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

STK36 Recombinant Protein Antigen - NBP1-83410PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

STK36 Peptide, Human - M34GP15318H from Creative Peptides Category Peptide Source Synthetic. Species Human

STK36 Immunizing peptide - orb16053 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Serine/threonine-protein kinase 36 (STK36), partial, Recombinant Protein - MBS1337460 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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