STK36

Gene Symbol STK36
Entrez Gene 27148
Alt Symbol FU
Species Human
Gene Type protein-coding
Description serine/threonine kinase 36
Other Description fused homolog|serine/threonine-protein kinase 36
Swissprots Q9ULE2 Q9UF35 B7WPM3 Q8TC32 Q9NRP7 Q9H9N9
Accessions CAC16640 EAW70647 EAW70648 EAW70649 EAW70650 Q9NRP7 AA524236 AA992176 AB033104 BAA86592 AF200815 AAF97028 AK022692 BAB14184 AL133630 CAB63754 BC026158 AAH26158 DB062910 DQ891739 ABM82665 DQ894916 ABM85842 XM_005246464 XP_005246521 XM_011510959 XP_011509261 XM_011510960 XP_011509262 XM_011510961 XP_011509263 XR_922904 NM_001243313 NP_001230242 NM_015690 NP_056505
Function Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. {ECO:0000269|PubMed:10806483}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10806483}. Nucleus {ECO:0000269|PubMed:10806483}. Note=Low levels also present in the nucleus.
Tissue Specificity Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis, where it is localized in germ cells. {ECO:0000269|PubMed:10806483}.
Top Pathways Hedgehog signaling pathway, Basal cell carcinoma

STK36 CRISPR/Cas9 KO Plasmid (h) - sc-409893 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 HDR Plasmid (h) - sc-409893-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 Double Nickase Plasmid (h) - sc-409893-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 Double Nickase Plasmid (h2) - sc-409893-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 CRISPR Activation Plasmid (h) - sc-409893-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 CRISPR Activation Plasmid (h2) - sc-409893-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 Lentiviral Activation Particles (h) - sc-409893-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 Lentiviral Activation Particles (h2) - sc-409893-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STK36 siRNA (h) - sc-95012 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STK36 shRNA Plasmid (h) - sc-95012-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STK36 shRNA (h) Lentiviral Particles - sc-95012-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STK36 RNAi - H00027148-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137991 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2186 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2188 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2187 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN20742 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05843 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05843

STK36 siRNA (Human) - CRH8994 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STK36 - MBS8217511 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human STK36 (NM_015690.4) - SHH419864 from Creative biogene

Category siRNA
Species Reactivities Human

STK36 shRNA Plasmid (Human) - CHH8994 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

STK36 miRNA 3'UTR clone - MiUTR3H-09369 from Creative biogene

Species Reactivities Human
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