SLC22A5

Gene Symbol SLC22A5
Entrez Gene 6584
Alt Symbol CDSP, OCTN2
Species Human
Gene Type protein-coding
Description solute carrier family 22 (organic cation/carnitine transporter), member 5
Other Description high-affinity sodium dependent carnitine cotransporter|organic cation/carnitine transporter 2|solute carrier family 22 member 5
Swissprots Q6ZQZ8 D3DQ87 O76082 Q96EH6 B2R844 A2Q0V1
Accessions BAA36712 CAX30725 EAW62337 EAW62338 EAW62339 O76082 AB015050 BAA29023 AB209484 BAD92721 AB291606 BAF45812 AF057164 AAC24828 AK128610 BAC87527 AK313230 BAG36041 AY429569 BC012325 AAH12325 BM693015 DA186237 DA567722 DQ893671 ABM84597 DQ895818 ABM86744 XM_005272055 XP_005272112 XM_011543590 XP_011541892 XR_427718 XR_948290 XR_948291 NM_001308122 NP_001295051 NM_003060 NP_003051
Function Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3. {ECO:0000269|PubMed:10454528}.
Subcellular Location Membrane {ECO:0000269|PubMed:10679939}; Multi-pass membrane protein {ECO:0000269|PubMed:10679939}.
Tissue Specificity Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. {ECO:0000269|PubMed:10454528}.
Top Pathways Choline metabolism in cancer

OCTN2 (H-102) - sc-368665 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

OCTN2 (H-13) - sc-19822 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OCTN2 (H-13): sc-19822. Western blot analysis of OCTN2 expression in human skeletal muscle (A), human kidney (B) and human placenta (C) tissue extracts and MCF7 whole cell lysate (D).

Anti-Solute carrier family 22 member 5 antibody - ab180757 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab180757. Blue DAPI for nuclear staining.

Anti-Solute carrier family 22 member 5 antibody - ab125416 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Solute carrier family 22 member 5 antibody (ab125416) at 1 µg/ml + OVCAR 3 lysate at 10 µg

Anti-SLC22A5 / OCTN2 Antibody (C-Terminus) - LS-C16935 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC22A5 / OCTN2 Antibody (C-Terminus) - LS-C16936 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC22A5 / OCTN2 Antibody (aa531-547) - LS-C313281 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of SLC22A5 / OCTN2 antibody. Lane 1: Rat Kidney Tissue Lysate. Lane 2: Rat Skeletal Muscles Tissue Lysate. Lane 3: Mouse Liver Tissue Lysate. Lane 4: HEPA Cell Lysate. Lane 5: NIH3T3 Cell Lysate.

Anti-SLC22A5 / OCTN2 Antibody (aa305-354) - LS-C146486 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLC22A5 antibody LS-C146486 Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.

Anti-SLC22A5 / OCTN2 Antibody (C-Terminus) - LS-C169746 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC22A5 / OCTN2 Antibody (aa282-331) IHC-plus™ - LS-B11435 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC22A5 / OCTN2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11435 concentration 20 ug/ml.

Anti-SLC22A5 / OCTN2 Antibody - LS-C192902 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of MCF-7 cell lines, using SLC22A5 antibody.

Anti-SLC22A5 / OCTN2 Antibody - LS-C335169 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of MCF7 cell using SLC22A5 antibody. Blue: DAPI for nuclear staining.

OCTN2/SLC22A5 Antibody - NBP2-39081 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: OCTN2/SLC22A5 Antibody [NBP2-39081] - Staining of human kidney shows moderate mebranous positivity in cells in tubules.

Slc22a5 Polyclonal Antibody - bs-8149R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC22A5 antibody produced in rabbit - SAB2107782 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC22A5: <B>Cat. No. SAB2107782</B>: Western blot analysis of SLC22A5 in OVCAR-3 with SLC22A5 (solute carrier family 22, organic cation/carnitine transporter, member 5) antibody against the C terminal of SLC22A5 (50 μg) antibody at 1.0 μg/mL.

Anti-SLC22A5 antibody produced in rabbit - SAB4300885 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC22A5 antibody - C-terminal region (ARP63404_P050) - ARP63404_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC22A5 Antibody - C-terminal region (ARP63405_P050) - ARP63405_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC22A5 Antibody (OAAF03968) - OAAF03968 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC22A5 Antibody (OAAF07123) - OAAF07123 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC22A5 antibody - 70R-20316 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SLC22A5 Polyclonal Antibody - A1676 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SLC22A5 antibody.

SLC22A5 Antibody - abx001408 from Abbexa

Host Rabbit
Clonality Polyclonal

SLC22A5 antibody - 16331-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human kidney tissue slide using 16331-1-AP( SLC22A5 Antibody) at dilution of 1:50 (under 10x lens)

Anti-SLC22A5 - 31-B6733 from ARP American Research Products

Prices $169.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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