SLC22A5

Gene Symbol	SLC22A5
Entrez Gene	6584
Alt Symbol	CDSP, OCTN2
Species	Human
Gene Type	protein-coding
Description	solute carrier family 22 (organic cation/carnitine transporter), member 5
Other Description	high-affinity sodium dependent carnitine cotransporter|organic cation/carnitine transporter 2|solute carrier family 22 member 5
Swissprots	Q6ZQZ8 D3DQ87 O76082 Q96EH6 B2R844 A2Q0V1
Accessions	BAA36712 CAX30725 EAW62337 EAW62338 EAW62339 O76082 AB015050 BAA29023 AB209484 BAD92721 AB291606 BAF45812 AF057164 AAC24828 AK128610 BAC87527 AK313230 BAG36041 AY429569 BC012325 AAH12325 BM693015 DA186237 DA567722 DQ893671 ABM84597 DQ895818 ABM86744 XM_005272055 XP_005272112 XM_011543590 XP_011541892 XR_427718 XR_948290 XR_948291 NM_001308122 NP_001295051 NM_003060 NP_003051
Function	Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3. {ECO:0000269|PubMed:10454528}.
Subcellular Location	Membrane {ECO:0000269|PubMed:10679939}; Multi-pass membrane protein {ECO:0000269|PubMed:10679939}.
Tissue Specificity	Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. {ECO:0000269|PubMed:10454528}.
Top Pathways	Choline metabolism in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Solute carrier family 22 member 5 full length protein - ab132872 from Abcam Category Protein Source Wheat germ Species Human

Human Solute carrier family 22 member 5 protein fragment - ab159540 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human OCTN2/SLC22A5 Protein - H00006584-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human OCTN2/SLC22A5 Protein - H00006584-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLC22A5-Antibody-C-term-Blocking-peptide - BP12694b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC22A5-Antibody-Center-Blocking-Peptide - BP8854c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC22A5 - H00006584-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLC22A5 - H00006584-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SLC22A5 - H00006584-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SLC22A5 - H00006584-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SLC22A5 fusion protein - ag9450 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SLC22A5 fusion protein - Ag9684 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

OCTN2/SLC22A5 Protein - NBP2-39081PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SLC22A5 Peptide, Human - M34GP14392H from Creative Peptides Category Peptide Source Synthetic. Species Human

OCTN2/SLC22A5 Recombinant Protein Antigen - NBP2-57222PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Solute carrier family 22 member 5 (SLC22A5), Recombinant Protein - MBS1095635 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human SLC22A5 Protein, GST-tagged - SLC22A5-668H from Creative Biomart Category Protein Source Wheat Germ Species Human

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