UBE2I

Gene Symbol	UBE2I
Entrez Gene	7329
Alt Symbol	C358B7.1, P18, UBC9
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2I
Other Description	SUMO-1-protein ligase|SUMO-conjugating enzyme UBC9|SUMO-protein ligase|ubiquitin carrier protein 9|ubiquitin carrier protein I|ubiquitin conjugating enzyme 9|ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)|ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9)|ubiquitin-conjugating enzyme UbcE2A|ubiquitin-like protein SUMO-1 conjugating enzyme|ubiquitin-protein ligase E2I|ubiquitin-protein ligase I
Swissprots	D3DU69 P63279 Q59GX1
Accessions	AAK61274 CBJ93564 CBK25700 EAW85673 EAW85674 EAW85675 EAW85676 EAW85677 EAW85678 EAW85679 P63279 AB208988 BAD92225 AJ002385 CAA05359 AK024172 AK093616 AK291118 BAF83807 AL833737 BC000427 AAH00427 BC000744 BC004429 AAH04429 BC004437 BC014997 BC051289 AAH51289 BC064492 BC069256 BE262845 BF315618 BG530957 BI523501 BI793063 BQ230918 BQ358820 BT006932 AAP35578 BT007010 AAP35656 BU146357 BU543455 CD249028 CX788607 D45050 BAA08091 DQ891373 ABM82299 DQ894552 ABM85478 U29092 AAC51361 U31882 AAC50603 U31933 AAB02181 U38785 AAB09410 U45328 AAA86662 U66818 AAC50715 U66867 AAC50716 X96427 CAA65287 XM_005255540 XP_005255597 XM_005255541 XP_005255598 XM_011522644 XP_011520946 XM_011522645 XP_011520947 NM_003345 NP_003336 NM_194259 NP_919235 NM_194260 NP_919236 NM_194261 NP_919237
Function	Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly- SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. {ECO:0000269|PubMed:11451954, ECO:0000269|PubMed:15809060, ECO:0000269|PubMed:17466333, ECO:0000269|PubMed:19638400, ECO:0000269|PubMed:19744555, ECO:0000269|PubMed:20077568, ECO:0000269|PubMed:8668529}.
Subcellular Location	Nucleus. Cytoplasm. Note=Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus. {ECO:0000269|PubMed:8610150}.
Top Pathways	Ubiquitin mediated proteolysis, RNA transport, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UBE2I / UBC9 ELISA Kit (Sandwich ELISA) - LS-F9693 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Human UBE2I / UBC9 ELISA Kit (Sandwich ELISA) - LS-F12891 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/nl Range 0.156-10 ng/ml

SUMO-conjugating enzyme UBC9 (UBE2I), Human, ELISA Kit - E01S0430 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

SUMO-conjugating enzyme UBC9, UBE2I, Human, ELISA Kit - E11134h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

SUMO conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7253244 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7224579 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7237654 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7217943 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7212058 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7208731 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7237180 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7235649 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7217474 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7211421 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SUMO-conjugating enzyme UBC9 (UBE2I), ELISA Kit - MBS7253486 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) , ELISA Kit - MBS9310711 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Ubiquitin Conjugating Enzyme E2I (UBE2I) - SEE600Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Rat UBE2I / UBC9 ELISA Kit (Custom ELISA) - LS-F16057 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Chicken UBE2I / UBC9 ELISA Kit (Custom ELISA) - LS-F16058 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse UBE2I / UBC9 ELISA Kit (Custom ELISA) - LS-F16056 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human SUMO-conjugating enzyme UBC9 ELISA Kit - abx250525 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human UBE2I ELISA Kit - abx153422 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

ELISA Kit for Ubiquitin Conjugating Enzyme E2I (UBE2I) - SEE600Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.125ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human SUMO-conjugating enzyme UBC9 ELISA Kit - EKE53780 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/ml Range 0.156-10 ng/mL

UBE2I - EKH2528 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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