Sp1

Gene Symbol Sp1
Entrez Gene 20683
Alt Symbol 1110003E12Rik, AA450830, AI845540, Sp1-1
Species Mouse
Gene Type protein-coding
Description trans-acting transcription factor 1
Other Description transcription factor Sp1
Swissprots Q64167 O89090 Q62251 O89087
Accessions CAA42721 EDL03985 O89090 AF022363 AAC08527 AF062566 AAC16484 AK003347 AK088458 BC165998 AAI65998 CF729889 CJ181598 EF200003 EF200004 EF200005 ABM98419 EF200006 EF200007 EF200008 EF200009 S79832 AAB35321 XM_011245533 XP_011243835 NM_013672 NP_038700
Function Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter Plays an essential role in the regulation of FE65 gene expression (By similarity). Positively regulates the transcription of the core clock component ARNTL/BMAL1. {ECO:0000250, ECO:0000269|PubMed:24030830}.
Subcellular Location Nucleus. Cytoplasm {ECO:0000250}. Note=Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location (By similarity). {ECO:0000250}.
Top Pathways TGF-beta signaling pathway, Huntington's disease, Estrogen signaling pathway, Choline metabolism in cancer, Transcriptional misregulation in cancer

Transcription factor Sp1 (SP1), Mouse, ELISA Kit - CSB-EL022438MO from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Sp1 transcription factor, ELISA Kit - MBS936605 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of mouse SP1 is typically less than 11.7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 46.88 pg/ml -3000 pg/ml.

Mouse Transcription factor Sp1(SP1) ELISA kit - CSB-EL022438MO from Cusabio

Category ELISA Kit
Sensitivity 11.7 pg/ml.
Range 46.88 pg/ml-3000 pg/ml

Mouse Transcription factor Sp1 (SP1) ELISA Kit - EKC37945 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 11.7 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Mouse Sp1 ELISA Kit - E064449 from Biobool

Category ELISA Kit

Mouse SP1 / PSbeta1-G ELISA Kit - E064455 from Biobool

Category ELISA Kit

SP1 ELISA Kit (Mouse) (OKCA01784) - OKCA01784 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 11.7 pg/mL
Range 46.88 - 3,000 pg/mL

Transcription factor Sp1, ELISA Kit - MBS2880424 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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