Gene Symbol | MSX2 |
---|---|
Entrez Gene | 4488 |
Alt Symbol | CRS2, FPP, HOX8, MSH, PFM, PFM1 |
Species | Human |
Gene Type | protein-coding |
Description | msh homeobox 2 |
Other Description | homeobox protein Hox-8|homeobox protein MSX-2|msh homeo box 2|msh homeobox homolog 2 |
Swissprots | P35548 Q53XM4 D3DQN1 Q9UD60 |
Accessions | AAB42178 AAD14169 CAL40519 EAW61381 EAW61382 P35548 AL552909 BC015509 AAH15509 BT009814 AAP88816 D14970 BAA03611 D26145 D31771 BAA06549 D89377 BAA13949 DQ891600 ABM82526 DQ894795 ABM85721 S75361 AAB33867 W38629 X69295 CAA49156 NM_002449 NP_002440 |
Function | Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter. {ECO:0000269|PubMed:12145306}. |
Subcellular Location | Nucleus. |
Top Pathways | HTLV-I infection |
Human Msx2/Hox8 full length protein - ab152544 from Abcam
|
||||||||||
Human Msx2/Hox8 peptide - ab86937 from Abcam
|
||||||||||
Human Msx2/Hox8 protein fragment - ab114704 from Abcam
|
||||||||||
MSX2 / MSH Antibody Blocking Peptide - LS-E3490 from LifeSpan Bioscience
|
||||||||||
MSX2 / MSH Antibody Blocking Peptide - LS-E10969 from LifeSpan Bioscience
|
||||||||||
MSX2 / MSH Antibody Blocking Peptide - LS-E7019 from LifeSpan Bioscience
|
||||||||||
MSX2 Recombinant Protein - H00004488-P01 from Novus Biologicals
|
||||||||||
Recombinant Human MSX2 Protein - H00004488-Q03 from Novus Biologicals
|
||||||||||
Msx2/Hox8 Peptide - P1193 from Novus Biologicals
|
||||||||||
MSX2-Antibody-Center-Blocking-Peptide - BP14677c from Abgent, a WuXi AppTec company
|
||||||||||
Msx2-Antibody-N-term-Blocking-Peptide - BP2709a from Abgent, a WuXi AppTec company
|
||||||||||
MSX2 - H00004488-P01 from Acris Antibodies
|
||||||||||
MSX2 - H00004488-Q03-10 from Acris Antibodies
|
||||||||||
MSX2 - H00004488-Q03-25 from Acris Antibodies
|
||||||||||
MSX2 fusion protein - Ag24385 from Proteintech Group
|
||||||||||
Recombinant Human MSX2 - MSX2-29500TH from Creative Biomart
|
||||||||||
Recombinant Human Homeobox protein MSX-2(MSX2) - CSB-YP015069HU CSB-EP015069HU CSB-BP015069HU CSB-MP015069HU from Cusabio
|
||||||||||
MSX2 Protein - abx164116 from Abbexa
|
||||||||||
MSX2 - TP302056 from Acris Antibodies
|
||||||||||
MSX2 Recombinant Protein Antigen - NBP1-85445PEP from Novus Biologicals
|
||||||||||
Msx2-Blocking-Peptide-C-term - BP2709B from Abgent, a WuXi AppTec company
|
||||||||||
MSX2 Peptide, Human - M34GP09846H from Creative Peptides
|
||||||||||
Homeobox protein MSX-2 (MSX2), Recombinant Protein - MBS954427 from MyBioSource
|