PRDM14

Gene Symbol	PRDM14
Entrez Gene	63978
Alt Symbol	PFM11
Species	Human
Gene Type	protein-coding
Description	PR domain containing 14
Other Description	PR domain zinc finger protein 14|PR domain-containing 14|PR domain-containing protein 14
Swissprots	Q86UX9 Q9GZV8
Accessions	EAW86962 Q9GZV8 AF319458 AAG39635 AK022595 BAB14120 BC052311 AAH52311 BF770200 CX166395 CX788380 EU446841 ABZ92370 HQ257953 ADR82707 KJ463837 AHX99430 XM_011517572 XP_011515874 NM_024504 NP_078780
Function	Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'. {ECO:0000250, ECO:0000269|PubMed:17942894, ECO:0000269|PubMed:20953172}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17942894}.
Tissue Specificity	Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level). {ECO:0000269|PubMed:17942894, ECO:0000269|PubMed:20953172}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PRDM14 full length protein - ab131985 from Abcam Category Protein Source Wheat germ Species Human

Human PRDM14 peptide - ab103275 from Abcam Category Peptide

Human PRDM14 protein fragment - ab196396 from Abcam Category Protein Source E. coli Species Human

PRDM14 Antibody Blocking Peptide - LS-E1447 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDM14 Antibody Blocking Peptide - LS-E27625 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRDM14 Antibody Blocking Peptide - LS-E27626 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PRDM14 Protein - H00063978-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PRDM14 Peptide - P0277 from Novus Biologicals Category Peptide Species Human

PRDM14-Antibody-N-term-Blocking-peptide - BP1214a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRDM14 Peptide - AC21-2443-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PRDM14 Peptide - AC21-2442-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PRDM14 / PFM11 - H00063978-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PRDM14 / PFM11 - H00063978-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PRDM14 Peptide - 42-423P from ProSci Category Peptide

PRDM14 fusion protein - ag18025 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant PRDM14 protein - 31397 from ActiveMotif Category Protein Prices $425.00 Sizes 20 µg Source Baculovirus Species Human

Recombinant Human PRDM14, FLAG-tagged - PRDM14-66H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant PR Domain Containing Protein 14 (PRDM14) - RPP332Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant PR Domain Containing Protein 14 (PRDM14) - RPP332Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human PR domain zinc finger protein 14(PRDM14) - CSB-YP863934HU CSB-EP863934HU CSB-BP863934HU CSB-MP863934HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PRDM14 / PFM11 - H00063978-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

PR domain zinc finger protein 14 (PRDM14), Recombinant Protein - MBS1418827 from MyBioSource Category Protein Prices $1,370.00, $1,370.00, $1,585.00, $1,585.00, $2,280.00, $2,280.00, $2,740.00, $2,740.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PRDM14, Peptide - MBS427524 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

PRDM14, Peptide - MBS427773 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

PRDM14 Recombinant Protein Antigen - NBP1-86437PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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