PRDM14

Gene Symbol PRDM14
Entrez Gene 63978
Alt Symbol PFM11
Species Human
Gene Type protein-coding
Description PR domain containing 14
Other Description PR domain zinc finger protein 14|PR domain-containing 14|PR domain-containing protein 14
Swissprots Q86UX9 Q9GZV8
Accessions EAW86962 Q9GZV8 AF319458 AAG39635 AK022595 BAB14120 BC052311 AAH52311 BF770200 CX166395 CX788380 EU446841 ABZ92370 HQ257953 ADR82707 KJ463837 AHX99430 XM_011517572 XP_011515874 NM_024504 NP_078780
Function Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'. {ECO:0000250, ECO:0000269|PubMed:17942894, ECO:0000269|PubMed:20953172}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17942894}.
Tissue Specificity Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level). {ECO:0000269|PubMed:17942894, ECO:0000269|PubMed:20953172}.

PRDM14 CRISPR/Cas9 KO Plasmid (h) - sc-404426 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 HDR Plasmid (h) - sc-404426-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 Double Nickase Plasmid (h) - sc-404426-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 Double Nickase Plasmid (h2) - sc-404426-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 CRISPR Activation Plasmid (h) - sc-404426-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 CRISPR Activation Plasmid (h2) - sc-404426-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 Lentiviral Activation Particles (h) - sc-404426-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 Lentiviral Activation Particles (h2) - sc-404426-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM14 siRNA (h) - sc-77737 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM14 shRNA Plasmid (h) - sc-77737-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM14 shRNA (h) Lentiviral Particles - sc-77737-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM14 RNAi - H00063978-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17372 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17372 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02613 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02613

PRDM14 siRNA (Human) - CRJ1890 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRDM14 (NM_024504.3) - SHH382196 from Creative biogene

Category siRNA
Species Reactivities Human

PRDM14 shRNA Plasmid (Human) - CHJ1890 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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