PDE8A

Gene Symbol PDE8A
Entrez Gene 5151
Alt Symbol HsT19550
Species Human
Gene Type protein-coding
Description phosphodiesterase 8A
Other Description cAMP-specific cyclic nucleotide phosphodiesterase 8A|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Swissprots Q96PC9 Q6P9H3 Q9UMC3 Q96T71 O60658 Q96PD0 Q9UMB7 B3KXE6 Q969I1 Q96PD1 H0YMZ7
Accessions EAX01965 EAX01966 EAX01967 EAX01968 EAX01969 EAX01970 O60658 AF056490 AAC39763 AF332653 AAK57641 AF388183 AAL18610 AF388184 AAL18611 AF388185 AAL18612 AF388186 AAL18613 AF388187 AAL18614 AI767983 AK074280 AK122689 BAG53669 AK127232 BAG54458 AL109687 CAB52020 AL109778 CAB52432 AL109789 CAB52453 BC013825 BC017164 BC036190 BC037260 BC048317 AAH48317 BC060762 AAH60762 BC075822 AAH75822 XM_005254933 XP_005254990 XM_006720568 XP_006720631 XM_011521667 XP_011519969 XM_011521668 XP_011519970 NM_001243137 NP_001230066 NM_002605 NP_002596 NM_173454 NP_775656 NM_173455 NM_173456 NM_173457
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. {ECO:0000269|PubMed:18983167}.
Tissue Specificity Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
Top Pathways Morphine addiction, Purine metabolism

PDE8A (C-15) - sc-17232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE8A (C-15): sc-17232. Western blot analysis of PDE8A expression in mouse ovary extract. Note splice variants.

PDE8A (H-64) - sc-30059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PDE8A (R-15) - sc-17231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE8A (R-15): sc-17231. Western blot analysis of PDE8A expression in mouse ovary extract. Note splice variants.

Anti-PDE8A antibody - ab14618 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE8A antibody - ab14619 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE8A antibody - ab109597 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PDE8A antibody (ab109597) at 0.1 µg/mlLane 1 : HeLa cell lysate at 50 µgLane 2 : HeLa cell lysate at 15 µgLane 3 : HeLa cell lysate at 5 µgLane 4 : 293T cell lysate at 50 µg

Anti-PDE8A antibody - ab77181 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-PDE8A antibody (ab77181) at 5 µg/ml + immunogen at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-PDE8A antibody - ab172067 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PDE8A antibody (ab172067) at 1/500 dilutionLane 1 : PDE8A transfected lysateLane 2 : Non-transfected lysateLysates/proteins at 15 µl per lane.

Anti-PDE8A antibody - ab61815 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of human Prostate tissue (Formalin-Fixed Paraffin-Embedded) using ab61815 at 10&microg/ml.

Anti-PDE8A antibody [EM52] - ab180628 from Abcam

Prices $357.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone EM52

Anti-PDE8A Antibody (C-Terminus) - LS-C90194 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (clone EM-52) - LS-C204343 from LifeSpan Bioscience

Prices $290.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone EM-52

Anti-PDE8A Antibody (Internal, AP) - LS-C265917 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, APC) - LS-C265918 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, Biotin) - LS-C265919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, FITC) - LS-C265920 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, Azide-free, HRP) - LS-C265921 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, PE) - LS-C265924 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, AP) - LS-C280827 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (aa681-730) - LS-C135468 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDE8A antibody LS-C135468 Western blot of Fetal Heart lysate.

Anti-PDE8A Antibody (aa551-600) - LS-C135467 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDE8A antibody LS-C135467 Western blot of PANC1 cell lysate.

Anti-PDE8A Antibody (Internal, PE) - LS-C280834 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, FITC) - LS-C280829 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, APC) - LS-C280828 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE8A Antibody (Internal, Azide-free, HRP) - LS-C280835 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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