PDE8A

Gene Symbol	PDE8A
Entrez Gene	5151
Alt Symbol	HsT19550
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 8A
Other Description	cAMP-specific cyclic nucleotide phosphodiesterase 8A|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Swissprots	Q96PC9 Q6P9H3 Q9UMC3 Q96T71 O60658 Q96PD0 Q9UMB7 B3KXE6 Q969I1 Q96PD1 H0YMZ7
Accessions	EAX01965 EAX01966 EAX01967 EAX01968 EAX01969 EAX01970 O60658 AF056490 AAC39763 AF332653 AAK57641 AF388183 AAL18610 AF388184 AAL18611 AF388185 AAL18612 AF388186 AAL18613 AF388187 AAL18614 AI767983 AK074280 AK122689 BAG53669 AK127232 BAG54458 AL109687 CAB52020 AL109778 CAB52432 AL109789 CAB52453 BC013825 BC017164 BC036190 BC037260 BC048317 AAH48317 BC060762 AAH60762 BC075822 AAH75822 XM_005254933 XP_005254990 XM_006720568 XP_006720631 XM_011521667 XP_011519969 XM_011521668 XP_011519970 NM_001243137 NP_001230066 NM_002605 NP_002596 NM_173454 NP_775656 NM_173455 NM_173456 NM_173457
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. {ECO:0000269|PubMed:18983167}.
Tissue Specificity	Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
Top Pathways	Morphine addiction, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDE8A full length protein - ab159077 from Abcam Category Protein Source Wheat germ Species Human

Human PDE8A protein fragment - ab114643 from Abcam Category Protein Source Wheat germ Species Human

PDE8A peptide - ab65452 from Abcam Category Peptide

PDE8A peptide - ab65448 from Abcam Category Peptide

PDE8A peptide - ab65450 from Abcam Category Peptide

PDE8A Antibody Blocking Peptide - LS-E3457 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE8A Antibody Blocking Peptide - LS-E21095 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE8A Antibody Blocking Peptide - LS-E21096 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE8A Antibody Blocking Peptide - LS-E29219 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PDE8A Protein - H00005151-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PDE8A Protein - H00005151-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PDE8A-Antibody-Center-L572-Blocking-Peptide - BP1463c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDE8A Blocking Peptide - 33R-8833 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDE8A Blocking Peptide - 33R-9815 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDE8A - H00005151-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PDE8A - H00005151-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PDE8A - H00005151-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PDE8A - H00005151-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PDE8A control peptide - AP10250CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE8A control peptide - AP10251CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE8A control peptide - AP10252CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

PDE8A fusion protein - Ag5192 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PDE8A fusion protein - ag5069 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PDE8A1, Active Human Recombinant Protein - GWB-60E572 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

Recombinant Human Phosphodiesterase 8A, GST-tagged, Active - PDE8A-482H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

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