PDE8A

Gene Symbol	PDE8A
Entrez Gene	5151
Alt Symbol	HsT19550
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 8A
Other Description	cAMP-specific cyclic nucleotide phosphodiesterase 8A|high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Swissprots	Q96PC9 Q6P9H3 Q9UMC3 Q96T71 O60658 Q96PD0 Q9UMB7 B3KXE6 Q969I1 Q96PD1 H0YMZ7
Accessions	EAX01965 EAX01966 EAX01967 EAX01968 EAX01969 EAX01970 O60658 AF056490 AAC39763 AF332653 AAK57641 AF388183 AAL18610 AF388184 AAL18611 AF388185 AAL18612 AF388186 AAL18613 AF388187 AAL18614 AI767983 AK074280 AK122689 BAG53669 AK127232 BAG54458 AL109687 CAB52020 AL109778 CAB52432 AL109789 CAB52453 BC013825 BC017164 BC036190 BC037260 BC048317 AAH48317 BC060762 AAH60762 BC075822 AAH75822 XM_005254933 XP_005254990 XM_006720568 XP_006720631 XM_011521667 XP_011519969 XM_011521668 XP_011519970 NM_001243137 NP_001230066 NM_002605 NP_002596 NM_173454 NP_775656 NM_173455 NM_173456 NM_173457
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. {ECO:0000269|PubMed:18983167}.
Tissue Specificity	Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
Top Pathways	Morphine addiction, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDE8A CRISPR/Cas9 KO Plasmid (h) - sc-403656 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A HDR Plasmid (h) - sc-403656-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A Double Nickase Plasmid (h) - sc-403656-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A Double Nickase Plasmid (h2) - sc-403656-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A CRISPR Activation Plasmid (h) - sc-403656-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A CRISPR Activation Plasmid (h2) - sc-403656-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A Lentiviral Activation Particles (h) - sc-403656-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A Lentiviral Activation Particles (h2) - sc-403656-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PDE8A siRNA (h) - sc-41617 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PDE8A shRNA Plasmid (h) - sc-41617-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PDE8A shRNA (h) Lentiviral Particles - sc-41617-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PDE8A RNAi - H00005151-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

PDE8A RNAi - H00005151-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PDE8A RNAi - H00005151-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PDE8A RNAi - H00005151-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU066731 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16547 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16547 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09020 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr09020

PDE8A siRNA (Human) - CRH3431 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PDE8A RNAi - H00005151-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PDE8A (NM_002605.2) - SHH372592 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PDE8A(NM_173454.1) - SHR100698 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PDE8A(NM_002605.2) - SHR100752 from Creative biogene Category siRNA Species Reactivities Human

Human PDE8A siRNA - orb263933 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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