NFAM1

Gene Symbol NFAM1
Entrez Gene 150372
Alt Symbol CNAIP, bK126B4.4
Species Human
Gene Type protein-coding
Description NFAT activating protein with ITAM motif 1
Other Description NFAT activation molecule 1|NFAT-activating protein with ITAM motif 1|calcinerin/NFAT-activating ITAM-containing protein|calcineurin/NFAT-activating ITAM-containing protein
Swissprots Q5JZ96 Q8TEM8 Q8NET5 Q8IUY8 Q20WL2 B0QYD0
Accessions EAW60504 EAW60505 Q8NET5 AK074094 BAB84920 AK097971 AY121370 AAM83133 AY247409 AAO91847 BC038241 AAH38241 CT841509 CAJ86439 CU013214 CAK54645 CU013502 CAK54944 XM_005261374 XP_005261431 XM_011529957 XP_011528259 XM_011529958 XP_011528260 NM_145912 NP_666017
Function May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross- linking. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Partially recruited to lipid rafts upon BCR stimulation. {ECO:0000250}.
Tissue Specificity Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.

NFAM1 (T-16) - sc-86182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
NFAM1 (T-16): sc-86182. Western blot analysis of NFAM1 expression in non-transfected 293T: sc-117752 (A), human NFAM1 transfected 293T: sc-115683 (B) and Jurkat (C) whole cell lysates.

NFAM1 (C-17) - sc-86180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-NFAM1 antibody - ab203206 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed and paraffin embedded Human lung carcinoma tissue labeling NFAM1 using ab203206 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-NFAM1 antibody - ab67662 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NFAM1 antibody (ab67662) at 1/500 dilutionLane 1 : NFAM1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-NFAM1 Antibody (aa250-265) - LS-C144075 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NFAM1 Antibody (aa250-265) - LS-C148183 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of NFAM1 in 1) transfected 293T cells and 2) untransfected 293T cells using LS-C148183 at 1:500.

NFAM1 Antibody - NBP2-24943 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NFAM1 Antibody [NBP2-24943] - Analysis of NFAM1 in 1) transfected 293T cells and 2) untransfected 293T cells using this antibody at 1:500.

NFAM1 Antibody (374301) - MAB4046 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 374301

NFAM1 Antibody - NBP1-84424 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NFAM1 Antibody [NBP1-84424] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

NFAM1 Antibody - H00150372-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: NFAM1 Antibody [H00150372-B01P] - Analysis of NFAM1 expression in transfected 293T cell line by NFAM1 polyclonal antibody. Lane 1: NFAM1 transfected lysate(29.7 KDa). Lane 2: Non-transfected lysate.

NFAM1 Antibody (2E9) - H00150372-M10 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E9

NFAM1 Polyclonal Antibody - bs-2680R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-2680P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\\nTMB staining;\\nRead the data in MicroplateReader by 450

Anti-NFAM1 (251-264) antibody produced in rabbit - SAB1103302 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NFAM1 was separated on SDS-PAGE, blotted with Anti-NFAM1 (251-264) (<B>Cat. No. SAB1103302</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + NFAM1 immunizing peptide (human, 251-264)

Anti-NFAM1 antibody produced in rabbit - HPA031812 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NFAM1: <B>Cat. No. HPA031812</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in tubular cells.

Anti-NFAM1 antibody produced in mouse - SAB1400819 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-NFAM1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400819</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

Anti-NFAM1 (208-220) antibody produced in rabbit - SAB1103301 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NFAM1 was separated on SDS-PAGE, blotted with Anti-NFAM1 (208-220) (<B>Cat. No. SAB1103301</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + NFAM1 immunizing peptide (human, 208-220)

NFAM1 antibody - GTX51546 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-NFAM1 antibody used in ELISA. GTX51546

Human NFAM1 Antibody - MAB4046 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 374301

Human NFAM1 MAb (Clone 374301), Mouse IgG2B - MAB4046-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 374301

NFAM1 Antibody (OABF01064) - OABF01064 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NFAM1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-2680R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NFAM1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-2680R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NFAM1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-2680R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NFAM1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-2680R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NFAM1 Polyclonal Antibody, Cy3 Conjugated - bs-2680R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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