NFAM1

Gene Symbol NFAM1
Entrez Gene 150372
Alt Symbol CNAIP, bK126B4.4
Species Human
Gene Type protein-coding
Description NFAT activating protein with ITAM motif 1
Other Description NFAT activation molecule 1|NFAT-activating protein with ITAM motif 1|calcinerin/NFAT-activating ITAM-containing protein|calcineurin/NFAT-activating ITAM-containing protein
Swissprots Q5JZ96 Q8TEM8 Q8NET5 Q8IUY8 Q20WL2 B0QYD0
Accessions EAW60504 EAW60505 Q8NET5 AK074094 BAB84920 AK097971 AY121370 AAM83133 AY247409 AAO91847 BC038241 AAH38241 CT841509 CAJ86439 CU013214 CAK54645 CU013502 CAK54944 XM_005261374 XP_005261431 XM_011529957 XP_011528259 XM_011529958 XP_011528260 NM_145912 NP_666017
Function May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross- linking. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Partially recruited to lipid rafts upon BCR stimulation. {ECO:0000250}.
Tissue Specificity Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.

Mouse NFAM1 ELISA Kit (Sandwich ELISA) - LS-F12146 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

NFAT activation molecule 1, NFAM1, Human, ELISA Kit - E3904h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t

NFAT activating protein with ITAM motif 1, ELISA Kit - MBS9316574 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human NFAM1 ELISA Kit (Custom ELISA) - LS-F19911 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Human NFAM1 ELISA Kit - E026468 from Biobool

Category ELISA Kit

NFAM1 ELISA Kit (Human) (OKEH05113) - OKEH05113 from Aviva Systems Biology

Category ELISA Kit
Prices $470.00
Sizes 96 wells
Sensitivity 0.078 ng/mL
Range 0.156-10 ng/mL

NFAT activation molecule 1, ELISA Kit - MBS2882456 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.156-10 ng/mL

NFAT activation molecule 1, ELISA Kit - MBS762282 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

Mouse NFAM1 ELISA Kit (Sandwich ELISA) - LS-F34250 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.094
Range 0.156-10 ng/ml
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