NFAM1

Gene Symbol	NFAM1
Entrez Gene	150372
Alt Symbol	CNAIP, bK126B4.4
Species	Human
Gene Type	protein-coding
Description	NFAT activating protein with ITAM motif 1
Other Description	NFAT activation molecule 1|NFAT-activating protein with ITAM motif 1|calcinerin/NFAT-activating ITAM-containing protein|calcineurin/NFAT-activating ITAM-containing protein
Swissprots	Q5JZ96 Q8TEM8 Q8NET5 Q8IUY8 Q20WL2 B0QYD0
Accessions	EAW60504 EAW60505 Q8NET5 AK074094 BAB84920 AK097971 AY121370 AAM83133 AY247409 AAO91847 BC038241 AAH38241 CT841509 CAJ86439 CU013214 CAK54645 CU013502 CAK54944 XM_005261374 XP_005261431 XM_011529957 XP_011528259 XM_011529958 XP_011528260 NM_145912 NP_666017
Function	May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross- linking. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Partially recruited to lipid rafts upon BCR stimulation. {ECO:0000250}.
Tissue Specificity	Highly expressed in neutrophils, primary monocytes, mast cells, monocytic cell lines and lymphocytes. Also expressed in spleen B and T-cells, and lung. Expressed at low level in non-immune tissue. {ECO:0000269|PubMed:12615919, ECO:0000269|PubMed:15143214}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NFAM1 full length protein - ab165609 from Abcam Category Protein Source Wheat germ Species Human

Human NFAM1 protein fragment - ab165610 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human NFAM1 Protein - H00150372-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NFAM1 Protein - H00150372-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NFAM1 - H00150372-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFAM1 - H00150372-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFAM1 - H00150372-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFAM1 - H00150372-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFAM1 fusion protein - Ag5359 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NFAM1 fusion protein - ag0970 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NFAM1 fusion protein - Ag5505 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NFAM1 fusion protein - ag8684 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NFAM1, GST-tagged - NFAM1-1272H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NFAT activation molecule 1(NFAM1) - CSB-YP850874HU CSB-EP850874HU CSB-BP850874HU CSB-MP850874HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NFAM1 Recombinant Protein Antigen - NBP1-84424PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NFAM1 Peptide, Human - M34GP10324H from Creative Peptides Category Peptide Source Synthetic. Species Human

NFAT activation molecule 1 (NFAM1), Recombinant Protein - MBS1405089 from MyBioSource Category Protein Prices $855.00, $855.00, $1,080.00, $1,080.00, $1,240.00, $1,240.00, $1,695.00, $1,695.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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