Gene Symbol |
SLC12A2
|
Entrez Gene |
6558
|
Alt Symbol |
BSC, BSC2, NKCC1, PPP1R141
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
|
Other Description |
basolateral Na-K-Cl symporter|bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1|protein phosphatase 1, regulatory subunit 141|solute carrier family 12 (sodium/potassium/chloride transporters), member 2|solute carrier family 12 member 2
|
Swissprots |
Q8N713 Q8WWH7 P55011
|
Accessions |
EAW62392 EAW62393 EAW62394 P55011 AA425438 AA425619 AA843086 AB209192 BAD92429 AF439152 AAL32454 AI493213 AK025062 AV708692 AY280459 AAP33906 BC033003 BC144221 AAI44222 BC146839 AAI46840 BM978607 U30246 AAC50561 Z36839 XM_011543588 XP_011541890 NM_001046 NP_001037 NM_001256461 NP_001243390 NR_046207
|
Function |
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in many tissues.
|
Top Pathways |
Vibrio cholerae infection, Salivary secretion, Pancreatic secretion
|