Gene Symbol | SLC12A2 |
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Entrez Gene | 6558 |
Alt Symbol | BSC, BSC2, NKCC1, PPP1R141 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
Other Description | basolateral Na-K-Cl symporter|bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1|protein phosphatase 1, regulatory subunit 141|solute carrier family 12 (sodium/potassium/chloride transporters), member 2|solute carrier family 12 member 2 |
Swissprots | Q8N713 Q8WWH7 P55011 |
Accessions | EAW62392 EAW62393 EAW62394 P55011 AA425438 AA425619 AA843086 AB209192 BAD92429 AF439152 AAL32454 AI493213 AK025062 AV708692 AY280459 AAP33906 BC033003 BC144221 AAI44222 BC146839 AAI46840 BM978607 U30246 AAC50561 Z36839 XM_011543588 XP_011541890 NM_001046 NP_001037 NM_001256461 NP_001243390 NR_046207 |
Function | Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in many tissues. |
Top Pathways | Vibrio cholerae infection, Salivary secretion, Pancreatic secretion |
NKCC1 Antibody - 4828 from Cell Signaling Technology
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NKCC1 (D13A9) Rabbit mAb - 8351 from Cell Signaling Technology
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NKCC1 (H-130) - sc-366921 from Santa Cruz Biotechnology
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NKCC1 (C-14) - sc-21547 from Santa Cruz Biotechnology
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NKCC1 (N-16) - sc-21545 from Santa Cruz Biotechnology
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Anti-NKCC1 antibody - ab59791 from Abcam
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Anti-NKCC1 antibody - ab191289 from Abcam
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Anti-NKCC1 antibody - ab104693 from Abcam
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Anti-NKCC1 antibody - ab133371 from Abcam
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Anti-NKCC1 antibody [5H7] - ab129308 from Abcam
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Anti-NKCC1 antibody - N-terminal - ab181763 from Abcam
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Anti-SLC12A2 / NKCC1 Antibody (aa223-241) - LS-C313276 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (Internal) IHC-plus⢠- LS-A8903 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (C-Terminus) - LS-C16865 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody - LS-C131056 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (N-Terminus) - LS-C153559 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (N-Terminus) - LS-C144699 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (aa769-783) IHC-plus⢠- LS-B5941 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (aa1101-1150) - LS-C40423 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (N-Terminus) - LS-C345424 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (clone 5H7) IHC-plus⢠- LS-B6385 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (C-Terminus) IHC-plus⢠- LS-A8904 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (Internal) IHC-plus⢠- LS-A8905 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (N-Terminus) IHC-plus⢠- LS-A8899 from LifeSpan Bioscience
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Anti-SLC12A2 / NKCC1 Antibody (C-Terminus) - LS-C16864 from LifeSpan Bioscience
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