Gene Symbol | SLC12A2 |
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Entrez Gene | 6558 |
Alt Symbol | BSC, BSC2, NKCC1, PPP1R141 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
Other Description | basolateral Na-K-Cl symporter|bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1|protein phosphatase 1, regulatory subunit 141|solute carrier family 12 (sodium/potassium/chloride transporters), member 2|solute carrier family 12 member 2 |
Swissprots | Q8N713 Q8WWH7 P55011 |
Accessions | EAW62392 EAW62393 EAW62394 P55011 AA425438 AA425619 AA843086 AB209192 BAD92429 AF439152 AAL32454 AI493213 AK025062 AV708692 AY280459 AAP33906 BC033003 BC144221 AAI44222 BC146839 AAI46840 BM978607 U30246 AAC50561 Z36839 XM_011543588 XP_011541890 NM_001046 NP_001037 NM_001256461 NP_001243390 NR_046207 |
Function | Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in many tissues. |
Top Pathways | Vibrio cholerae infection, Salivary secretion, Pancreatic secretion |
Human NKCC1 protein fragment - ab159532 from Abcam
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NKCC1 peptide - ab134010 from Abcam
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E16102 from LifeSpan Bioscience
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E27251 from LifeSpan Bioscience
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E29512 from LifeSpan Bioscience
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E29511 from LifeSpan Bioscience
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E29513 from LifeSpan Bioscience
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SLC12A2 / NKCC1 Antibody Blocking Peptide - LS-E29514 from LifeSpan Bioscience
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Recombinant Human NKCC1/SLC12A2 Protein - H00006558-Q01 from Novus Biologicals
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SLC12A2-Antibody-C-term-Blocking-Peptide - BP17792b from Abgent, a WuXi AppTec company
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SLC12A2 blocking peptide - GTX88157-PEP from GeneTex
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SLC12A2 Blocking Peptide - 33R-3991 from Fitzgerald
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NKCC1 Peptide - AC21-2072-P from Abcore
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SLC12A2 / NKCC1 - H00006558-Q01-10 from Acris Antibodies
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SLC12A2 / NKCC1 - H00006558-Q01-25 from Acris Antibodies
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SLC12A2 Peptide - 42-498P from ProSci
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SLC12A2 fusion protein - ag4991 from Proteintech Group
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SLC12A2, Peptide - MBS427191 from MyBioSource
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NKCC1/SLC12A2 Recombinant Protein Antigen - NBP1-89928PEP from Novus Biologicals
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SLC12A2 Peptide, Human - M34GP14315H from Creative Peptides
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NKCC1/SLC12A2 Recombinant Protein Antigen - NBP2-56180PEP from Novus Biologicals
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Solute carrier family 12 member 2 (SLC12A2), partial, Recombinant Protein - MBS960013 from MyBioSource
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SLC12A2 fusion protein - Ag27895 from Proteintech Group
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