NIT1

Gene Symbol NIT1
Entrez Gene 4817
Alt Symbol -
Species Human
Gene Type protein-coding
Description nitrilase 1
Other Description nitrilase homolog 1
Swissprots D3DVF4 B1AQP3 O76091 Q86X76
Accessions AAC39901 EAW52654 EAW52655 EAW52656 EAW52657 Q86X76 AF069987 AAC39907 AI277603 AK296606 BAH12396 AK313323 BAG36128 AY893504 AAX36541 AY893938 AAX36975 BC046149 AAH46149 BI752623 BQ002524 BX416745 CB111935 CR541814 CAG46613 CR541846 CAG46644 DC302367 XM_005245214 XP_005245271 XM_005245215 XP_005245272 XM_005245216 XP_005245273 XM_006711341 XP_006711404 NM_001185092 NP_001172021 NM_001185093 NP_001172022 NM_001185094 NP_001172023 NM_005600 NP_005591
Function Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Mitochondrion {ECO:0000250}.
Tissue Specificity Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9671749}.

Human NIT1 Gene cDNA Clone - orb144450 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

NIT1 - MBS1274722 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC046149

Human NIT1 ORF Clone (BC046149) - CDCS409183 from Creative biogene

Species Human
Accession Q86X76

Human NIT1 ORF clone (BC046149) - CDCB159734 from Creative biogene

Species Human
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