NIT1

Gene Symbol NIT1
Entrez Gene 4817
Alt Symbol -
Species Human
Gene Type protein-coding
Description nitrilase 1
Other Description nitrilase homolog 1
Swissprots D3DVF4 B1AQP3 O76091 Q86X76
Accessions AAC39901 EAW52654 EAW52655 EAW52656 EAW52657 Q86X76 AF069987 AAC39907 AI277603 AK296606 BAH12396 AK313323 BAG36128 AY893504 AAX36541 AY893938 AAX36975 BC046149 AAH46149 BI752623 BQ002524 BX416745 CB111935 CR541814 CAG46613 CR541846 CAG46644 DC302367 XM_005245214 XP_005245271 XM_005245215 XP_005245272 XM_005245216 XP_005245273 XM_006711341 XP_006711404 NM_001185092 NP_001172021 NM_001185093 NP_001172022 NM_001185094 NP_001172023 NM_005600 NP_005591
Function Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Mitochondrion {ECO:0000250}.
Tissue Specificity Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9671749}.

NIT1 CRISPR/Cas9 KO Plasmid (h) - sc-416332 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 HDR Plasmid (h) - sc-416332-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 Double Nickase Plasmid (h) - sc-416332-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 Double Nickase Plasmid (h2) - sc-416332-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 CRISPR Activation Plasmid (h) - sc-416332-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 CRISPR Activation Plasmid (h2) - sc-416332-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 Lentiviral Activation Particles (h) - sc-416332-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 Lentiviral Activation Particles (h2) - sc-416332-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NIT1 siRNA (h) - sc-78620 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIT1 shRNA Plasmid (h) - sc-78620-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NIT1 shRNA (h) Lentiviral Particles - sc-78620-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU030711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15311 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15311 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02027 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02027

NIT1 siRNA (Human) - CRH3198 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NIT1 shRNA Plasmid (Human) - CHH3198 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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