PAPD5

Gene Symbol	PAPD5
Entrez Gene	64282
Alt Symbol	TRF4-2
Species	Human
Gene Type	protein-coding
Description	PAP associated domain containing 5
Other Description	PAP-associated domain-containing protein 5|TUTase 3|non-canonical poly(A) RNA polymerase PAPD5|terminal uridylyltransferase 3|topoisomerase-related function protein 4-2
Swissprots	Q9Y6C0 Q9NW67 B4DV38 Q8NDF8
Accessions	EAW82747 EAW82748 EAW82749 EAW82750 Q8NDF8 AF089897 AAD45199 AK001141 BAA91518 AK097589 AK098806 AK223410 BAD97130 AK299294 BAG61309 AK300918 BAG62550 AL833922 CAD38778 BC035270 BC089405 AAH89405 BC143706 AAI43707 BC156329 AAI56330 BC157079 AAI57080 DN994465 FR872509 CCB84642 XM_005256092 XP_005256149 XM_005256093 XP_005256150 XM_011523275 XP_011521577 XM_011523276 XP_011521578 XM_011523277 XP_011521579 XM_011523278 XP_011521580 NM_022447 NM_001040284 NP_001035374 NM_001040285 NP_001035375
Function	Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. {ECO:0000269|PubMed:18172165, ECO:0000269|PubMed:21788334}.
Subcellular Location	Nucleus, nucleolus. Cytoplasm. Note=Predominantly expressed in the cytoplasm.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRF4-2 peptide - ab22950 from Abcam Category Peptide Species Human

PAPD5 Antibody Blocking Peptide - LS-E5874 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAPD5 Antibody Blocking Peptide - LS-E27664 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAPD5 Antibody Blocking Peptide - LS-E27692 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAPD5-Antibody-N-term-Blocking-Peptide - BP18427a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PAPD5 blocking peptide - GTX89894-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

TRF4-2 Peptide - AC21-2482-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRF4-2 Peptide - AC21-2508-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PAPD5 / TRF4-2 - H00064282-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PAPD5 / TRF4-2 - H00064282-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PAPD5 Peptide - 42-370P from ProSci Category Peptide Species Human, Mouse

PAPD5 Peptide - 42-364P from ProSci Category Peptide Species Mouse, Rat

Recombinant Human PAP-associated domain-containing protein 5(PAPD5) - CSB-YP843329HU CSB-EP843329HU CSB-BP843329HU CSB-MP843329HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PAP-associated domain-containing protein 5 (PAPD5), Recombinant Protein - MBS1311111 from MyBioSource Category Protein Prices $995.00, $1,055.00, $1,185.00, $1,340.00, $1,435.00, $1,435.00, $1,475.00, $1,500.00, $1,620.00, $2,100.00, $2,150.00, $2,160.00, $2,470.00, $2,820.00 Sizes 50 µg (E-Coli), 50 µg (Yeast), 50 µg (Baculovirus), 200 µg (E-Coli), 50 µg (Mammalian-Cell), 200 µg (Yeast), 500 µg (E-Coli), 100 µg (Baculovirus), 500 µg (Yeast), 1 mg (E-Coli), 500 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PAPD5, Peptide - MBS428295 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

PAPD5, Peptide - MBS427419 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

PAPD5 Recombinant Protein Antigen - NBP2-48777PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

PAPD5 Peptide, Human - M34GP11284H from Creative Peptides Category Peptide Source Synthetic. Species Human

PAPD5 Recombinant Protein Antigen - NBP2-48896PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

PAPD5 Immunizing peptide - orb66146 from Biorbyt Category Peptide

PAPD5 Immunizing peptide - orb15556 from Biorbyt Category Peptide

Recombinant Human PAPD5 Protein (1-572 aa), His-SUMO-tagged - PAPD5-2524H from Creative Biomart Category Protein Source E. coli Species Human

Search more