PAPD5

Gene Symbol PAPD5
Entrez Gene 64282
Alt Symbol TRF4-2
Species Human
Gene Type protein-coding
Description PAP associated domain containing 5
Other Description PAP-associated domain-containing protein 5|TUTase 3|non-canonical poly(A) RNA polymerase PAPD5|terminal uridylyltransferase 3|topoisomerase-related function protein 4-2
Swissprots Q9Y6C0 Q9NW67 B4DV38 Q8NDF8
Accessions EAW82747 EAW82748 EAW82749 EAW82750 Q8NDF8 AF089897 AAD45199 AK001141 BAA91518 AK097589 AK098806 AK223410 BAD97130 AK299294 BAG61309 AK300918 BAG62550 AL833922 CAD38778 BC035270 BC089405 AAH89405 BC143706 AAI43707 BC156329 AAI56330 BC157079 AAI57080 DN994465 FR872509 CCB84642 XM_005256092 XP_005256149 XM_005256093 XP_005256150 XM_011523275 XP_011521577 XM_011523276 XP_011521578 XM_011523277 XP_011521579 XM_011523278 XP_011521580 NM_022447 NM_001040284 NP_001035374 NM_001040285 NP_001035375
Function Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. {ECO:0000269|PubMed:18172165, ECO:0000269|PubMed:21788334}.
Subcellular Location Nucleus, nucleolus. Cytoplasm. Note=Predominantly expressed in the cytoplasm.
Top Pathways RNA degradation

PAPD5 CRISPR/Cas9 KO Plasmid (h) - sc-412997 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 HDR Plasmid (h) - sc-412997-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 Double Nickase Plasmid (h) - sc-412997-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 Double Nickase Plasmid (h2) - sc-412997-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 CRISPR Activation Plasmid (h) - sc-412997-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 CRISPR Activation Plasmid (h2) - sc-412997-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 Lentiviral Activation Particles (h) - sc-412997-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 Lentiviral Activation Particles (h2) - sc-412997-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD5 siRNA (h) - sc-93016 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD5 shRNA Plasmid (h) - sc-93016-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD5 shRNA (h) Lentiviral Particles - sc-93016-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD5 RNAi - H00064282-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU087861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16312 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16312 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PAPD5 siRNA (Human) - CRJ1975 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PAPD5 (NM_001040284.2) - SHH370460 from Creative biogene

Category siRNA
Species Reactivities Human

PAPD5 shRNA Plasmid (Human) - CHJ1975 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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