PTH2

Gene Symbol PTH2
Entrez Gene 113091
Alt Symbol TIP39
Species Human
Gene Type protein-coding
Description parathyroid hormone 2
Other Description tuberoinfundibular 39 residue protein|tuberoinfundibular 39 residues|tuberoinfundibular peptide of 39 residues
Swissprots Q96DJ4 Q96A98
Accessions EAW52480 Q96A98 AY037555 AAK68689 AY048588 AAL06597 BC093995 AAH93995 BC093997 AAH93997 XM_011526409 XP_011524711 NM_178449 NP_848544
Function Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits. {ECO:0000269|PubMed:11861531, ECO:0000269|PubMed:12559132, ECO:0000269|PubMed:12754053, ECO:0000269|PubMed:14988434}.
Subcellular Location Secreted.
Tissue Specificity Highly expressed in fetal and adult brain, cerebellum and trachea. Weakly expressed in spinal cord, fetal liver, kidney and heart. {ECO:0000269|PubMed:12098667}.

TIP39 CRISPR/Cas9 KO Plasmid (h) - sc-405791 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 HDR Plasmid (h) - sc-405791-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 Double Nickase Plasmid (h) - sc-405791-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 Double Nickase Plasmid (h2) - sc-405791-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 CRISPR Activation Plasmid (h) - sc-405791-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 CRISPR Activation Plasmid (h2) - sc-405791-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 Lentiviral Activation Particles (h) - sc-405791-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 Lentiviral Activation Particles (h2) - sc-405791-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17679 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17679 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PTH2 siRNA (Human) - CRJ4307 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PTH2 (NM_178449.3) - SHH386184 from Creative biogene

Category siRNA
Species Reactivities Human

TIP39 CRISPR/Cas9 KO Plasmid (h2) - sc-405791-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIP39 HDR Plasmid (h2) - sc-405791-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human PTH2 siRNA - orb274808 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTH2 shRNA Plasmid (Human) - CHJ4307 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTH2 miRNA 3'UTR clone - MiUTR4H-TG07193 from Creative biogene

Species Reactivities Human
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