RBM5

Gene Symbol RBM5
Entrez Gene 10181
Alt Symbol G15, H37, LUCA15, RMB5
Species Human
Gene Type protein-coding
Description RNA binding motif protein 5
Other Description RNA-binding protein 5|putative tumor suppressor LUCA15|renal carcinoma antigen NY-REN-9
Swissprots Q9UKY8 P52756 Q9BU14 Q93021 B4DMF9 Q9UL24 B4DM16 B2RA45 Q9HDA6 B4DZ63
Accessions AAB42216 EAW65040 EAW65041 EAW65042 P52756 AB208813 BAD92050 AB586690 BAJ19019 AF091263 AAD04159 AF103802 AAF02422 AF107493 AAF99551 AK097195 AK297249 BAG59728 AK297445 BAG59871 AK302766 BAG63975 AK314032 BAG36742 AL701303 AU129811 BC002957 BC156348 AAI56349 BC157102 AAI57103 BM985111 BQ899199 BX441555 CN293007 DA776815 DB080737 DR762951 U23946 AAA99715 XM_006712917 XP_006712980 XM_006712919 XP_006712982 XM_011533261 XP_011531563 XM_011533262 XP_011531564 XR_427245 NM_005778 NP_005769 NR_036627
Function Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. {ECO:0000269|PubMed:10949932, ECO:0000269|PubMed:12207175, ECO:0000269|PubMed:12581154, ECO:0000269|PubMed:15192330, ECO:0000269|PubMed:16585163, ECO:0000269|PubMed:18840686, ECO:0000269|PubMed:18851835}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18851835}.
Tissue Specificity Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.

LUCA15 (D-15) - sc-15473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LUCA15 (D-15): sc-15473. Western blot analysis of LUCA15 expression in HUV-EC-C whole cell lysate.

LUCA15 (S-19) - sc-15474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LUCA15 (S-19): sc-15474. Immunoperoxidase staining of formalin fixed, paraffin-embedded human naso-pharynx tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.

LUCA15 (17-JJ) - sc-100966 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
LUCA15 (17-JJ): sc-100966. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tissue showing nuclear localization.

Anti-RBM5 antibody [2B6] - ab115733 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
ab115733 at 5ug/ml staining RBM5 in Human placenta tissue by immunohistochemistry Formalin-Fixed, Paraffin-Embedded (FFPE).

Anti-RBM5 antibody - ab69770 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Left: human brain tissue stained with ab69770 at 1/50 dilution; Right: the antibody was preincubated with the immunizing peptide.

Anti-RBM5 antibody - ab56598 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RBM5 antibody (ab56598) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.

Anti-RBM5 / G15 Antibody (clone 2B6) IHC-plus™ - LS-B4492 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
Anti-RBM5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4492 concentration 5 ug/ml.

Anti-RBM5 / G15 Antibody (aa17-46, AP) - LS-C267939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa17-46, APC) - LS-C267940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa17-46, Biotin) - LS-C267941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa17-46, FITC) - LS-C267942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa17-46, Azide-free, HRP) - LS-C267943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa17-46, PE) - LS-C267944 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (N-Terminus) - LS-C101704 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
RBM5 antibody LS-C101704 Western blot of HepG2 cell lysate.

Anti-RBM5 / G15 Antibody (aa75-184, Azide-free) - LS-C328556 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RBM5 / G15 Antibody (aa17-46) - LS-C330054 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa765-815) - LS-C288983 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RBM5 / G15 Antibody (aa18-46) - LS-C162504 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RBM5 Antibody western blot of A549 cell line lysates (35 ug/lane). The RBM5 antibody detected the RBM5 protein (arrow).

Anti-RBM5 / G15 Antibody (aa226-275) - LS-C118933 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using RBM5 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-RBM5 / G15 Antibody (Asn261) - LS-C177017 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of LUCA15 (N261) pAb in paraffin-embedded human brain tissue.

RBM5 Antibody - NBP1-83305 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RBM5 Antibody [NBP1-83305] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

RBM5 Antibody - NBP1-83304 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RBM5 Antibody [NBP1-83304] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

RBM5 Antibody - H00010181-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RBM5 Antibody [H00010181-B01] - analysis of RBM5 expression in transfected 293T cell line by RBM5 MaxPab polyclonal antibody (B01). Lane 1: RBM5 transfected lysate (61.50 KDa). Lane 2: Non-transfected lysate.

RBM5 Antibody (2B6) - H00010181-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
Western Blot: RBM5 Antibody (2B6) [H00010181-M01] - Analysis of RBM5 over-expressed 293 cell line, cotransfected with RBM5 Validated Chimera RNAi ( Cat # H00010181-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with RBM5 monoclonal antibody (M01), clone 2B6 (Cat # H00010181-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

RBM5 Antibody - H00010181-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RBM5 Antibody [H00010181-B01P] - Analysis of RBM5 expression in transfected 293T cell line by RBM5 polyclonal antibody. Lane 1: RBM5 transfected lysate(60.06 KDa). Lane 2: Non-transfected lysate.
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