RBM5

Gene Symbol	RBM5
Entrez Gene	10181
Alt Symbol	G15, H37, LUCA15, RMB5
Species	Human
Gene Type	protein-coding
Description	RNA binding motif protein 5
Other Description	RNA-binding protein 5|putative tumor suppressor LUCA15|renal carcinoma antigen NY-REN-9
Swissprots	Q9UKY8 P52756 Q9BU14 Q93021 B4DMF9 Q9UL24 B4DM16 B2RA45 Q9HDA6 B4DZ63
Accessions	AAB42216 EAW65040 EAW65041 EAW65042 P52756 AB208813 BAD92050 AB586690 BAJ19019 AF091263 AAD04159 AF103802 AAF02422 AF107493 AAF99551 AK097195 AK297249 BAG59728 AK297445 BAG59871 AK302766 BAG63975 AK314032 BAG36742 AL701303 AU129811 BC002957 BC156348 AAI56349 BC157102 AAI57103 BM985111 BQ899199 BX441555 CN293007 DA776815 DB080737 DR762951 U23946 AAA99715 XM_006712917 XP_006712980 XM_006712919 XP_006712982 XM_011533261 XP_011531563 XM_011533262 XP_011531564 XR_427245 NM_005778 NP_005769 NR_036627
Function	Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. {ECO:0000269|PubMed:10949932, ECO:0000269|PubMed:12207175, ECO:0000269|PubMed:12581154, ECO:0000269|PubMed:15192330, ECO:0000269|PubMed:16585163, ECO:0000269|PubMed:18840686, ECO:0000269|PubMed:18851835}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:18851835}.
Tissue Specificity	Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RBM5 protein fragment - ab132608 from Abcam Category Protein Source Wheat germ Species Human

RBM5 / G15 Antibody Blocking Peptide - LS-E3697 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RBM5 / G15 Antibody Blocking Peptide - LS-E13926 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RBM5 Protein - H00010181-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human RBM5 Protein - H00010181-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RBM5-Antibody-N-term-Blocking-Peptide - BP14901c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RBM5 Blocking Peptide - 33R-3553 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RBM5 / LUCA15 - H00010181-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RBM5 / LUCA15 - H00010181-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RBM5 / LUCA15 - H00010181-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RBM5 / LUCA15 - H00010181-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RBM5 fusion protein - Ag13908 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RBM5 fusion protein - Ag14029 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human RBM5, His-tagged - RBM5-31232TH from Creative Biomart Category Protein Source E. coli

Recombinant Human RBM5, GST-tagged - RBM5-2217H from Creative Biomart Category Protein Source E.coli Species Human

LUCA15 (N261) Peptide - BS2476P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human RNA-binding protein 5(RBM5) ,partial - CSB-YP019434HU CSB-EP019434HU CSB-BP019434HU CSB-MP019434HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

G15 Blocking Peptide - CBP4194 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

G15 Blocking Peptide - abx161405 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

RBM5 / LUCA15 - TP312543 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RBM5 Recombinant Protein Antigen - NBP1-83305PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RBM5 Recombinant Protein Antigen - NBP1-83304PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RBM5 Peptide, Human - M34GP13075H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNA-binding protein 5 (RBM5), partial, Recombinant Protein - MBS953953 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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