KLF4

Gene Symbol KLF4
Entrez Gene 9314
Alt Symbol EZF, GKLF
Species Human
Gene Type protein-coding
Description Kruppel-like factor 4 (gut)
Other Description Krueppel-like factor 4|endothelial Kruppel-like zinc finger protein|epithelial zinc finger protein EZF|gut-enriched krueppel-like factor
Swissprots B2R8S4 O43474 L0R4N5 Q9UNP3 Q5T3J9 Q5T3J8 L0R3I6 P78338 Q8N717 B3KT79
Accessions ABG25917 CDM21965 EAW59019 EAW59020 EAW59021 O43474 AF022184 AAC03462 AF105036 AAD42165 AK095134 BAG52991 AK095894 AK313489 BAG36271 BC029923 AAH29923 BC030811 AAH30811 BU739190 DN995850 DQ891793 ABM82719 DQ894975 ABM85901 HF546201 CCO02787 HF546202 CCO02788 HF546213 CCO02799 HM026463 ADL14248 U70663 AAB48399 XM_005252305 XP_005252362 NM_004235 NP_004226
Function Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. {ECO:0000269|PubMed:17308127, ECO:0000269|PubMed:20071344}.
Subcellular Location Nucleus.
Top Pathways Signaling pathways regulating pluripotency of stem cells

KLF4-Over-expression-Lysate - LY11530a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag KLF4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KLF4 gene

KLF4 293T Cell Transient Overexpression Lysate(Denatured) - H00009314-T02 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

KLF4 overexpression lysate - LY401356 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

KLF4 overexpression lysate - LY432255 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

KLF4 293 Cell Lysate - 401238 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

KLF4 Overexpression Lysate (Native) - NBL1-12320 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: KLF4 Overexpression Lysate (Adult Normal) [NBL1-12320] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KLF4.

GKLF (h): 293T Lysate - sc-114641 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

KLF4 Over-expression Lysate Product - GWB-305623 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

KLF4 Overexpression Lysate (Native) - NBP2-10234 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

KLF4 Overexpression Lysate (Denatured) - H00009314-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human KLF4 Knockdown Stable Cell Line - CSC-DC008252 from Creative biogene

Category Cell Line
Species Human

Human KLF4 Knockout Cell Line-HeLa - CSC-RT0769 from Creative biogene

Category Cell Line
Species Human

KLF4 KO Cell Lysate-HeLa - CLKO-0273 from Creative biogene

Category Cell Lysate
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