KLF4

Gene Symbol KLF4
Entrez Gene 9314
Alt Symbol EZF, GKLF
Species Human
Gene Type protein-coding
Description Kruppel-like factor 4 (gut)
Other Description Krueppel-like factor 4|endothelial Kruppel-like zinc finger protein|epithelial zinc finger protein EZF|gut-enriched krueppel-like factor
Swissprots B2R8S4 O43474 L0R4N5 Q9UNP3 Q5T3J9 Q5T3J8 L0R3I6 P78338 Q8N717 B3KT79
Accessions ABG25917 CDM21965 EAW59019 EAW59020 EAW59021 O43474 AF022184 AAC03462 AF105036 AAD42165 AK095134 BAG52991 AK095894 AK313489 BAG36271 BC029923 AAH29923 BC030811 AAH30811 BU739190 DN995850 DQ891793 ABM82719 DQ894975 ABM85901 HF546201 CCO02787 HF546202 CCO02788 HF546213 CCO02799 HM026463 ADL14248 U70663 AAB48399 XM_005252305 XP_005252362 NM_004235 NP_004226
Function Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. {ECO:0000269|PubMed:17308127, ECO:0000269|PubMed:20071344}.
Subcellular Location Nucleus.
Top Pathways Signaling pathways regulating pluripotency of stem cells

GKLF CRISPR/Cas9 KO Plasmid (h) - sc-400312 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF HDR Plasmid (h) - sc-400312-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF Double Nickase Plasmid (h) - sc-400312-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF Double Nickase Plasmid (h2) - sc-400312-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF CRISPR Activation Plasmid (h) - sc-400312-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF CRISPR Activation Plasmid (h2) - sc-400312-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF Lentiviral Activation Particles (h) - sc-400312-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF Lentiviral Activation Particles (h2) - sc-400312-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GKLF siRNA (h) - sc-35480 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GKLF shRNA Plasmid (h) - sc-35480-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GKLF shRNA (h) Lentiviral Particles - sc-35480-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KLF4 RNAi - H00009314-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU151801 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1504 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1504 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06670 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06670

KLF4 siRNA (Human) - CRH6161 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KLF4 (NM_004235.4) - SHH325831 from Creative biogene

Category siRNA
Species Reactivities Human

Human KLF4 siRNA - orb266663 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KLF4 shRNA Plasmid (Human) - CHH6161 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KLF4 miRNA 3'UTR clone - MiUTR3H-04817 from Creative biogene

Species Reactivities Human
Search more