KLF4

Gene Symbol	KLF4
Entrez Gene	9314
Alt Symbol	EZF, GKLF
Species	Human
Gene Type	protein-coding
Description	Kruppel-like factor 4 (gut)
Other Description	Krueppel-like factor 4|endothelial Kruppel-like zinc finger protein|epithelial zinc finger protein EZF|gut-enriched krueppel-like factor
Swissprots	B2R8S4 O43474 L0R4N5 Q9UNP3 Q5T3J9 Q5T3J8 L0R3I6 P78338 Q8N717 B3KT79
Accessions	ABG25917 CDM21965 EAW59019 EAW59020 EAW59021 O43474 AF022184 AAC03462 AF105036 AAD42165 AK095134 BAG52991 AK095894 AK313489 BAG36271 BC029923 AAH29923 BC030811 AAH30811 BU739190 DN995850 DQ891793 ABM82719 DQ894975 ABM85901 HF546201 CCO02787 HF546202 CCO02788 HF546213 CCO02799 HM026463 ADL14248 U70663 AAB48399 XM_005252305 XP_005252362 NM_004235 NP_004226
Function	Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. {ECO:0000269|PubMed:17308127, ECO:0000269|PubMed:20071344}.
Subcellular Location	Nucleus.
Top Pathways	Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human KLF4 full length protein - ab169841 from Abcam Category Protein Prices $302.00 Sizes 50 µg Source E. coli Species Human

Human KLF4 protein fragment - ab132932 from Abcam Category Protein Source Wheat germ Species Human

Human KLF4 protein fragment - ab203545 from Abcam Category Protein Source E. coli Species Human

Human KLF4 protein fragment - ab109935 from Abcam Category Protein Source E. coli Species Human

Human KLF4 protein fragment - ab91256 from Abcam Category Protein Source HEK 293 cells Species Human

KLF4 peptide - ab187962 from Abcam Category Peptide

KLF4 Antibody Blocking Peptide - LS-E1328 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E25371 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E30863 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KLF4 Antibody Blocking Peptide - LS-E7448 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E7042 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E7043 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E7044 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E13810 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E12695 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Antibody Blocking Peptide - LS-E13304 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLF4 Recombinant Protein - H00009314-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

KLF4 Partial Recombinant Protein - H00009314-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

KLF4 Blocking Peptide - NBP1-77382PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human KLF4 Protein - NBP1-72390 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

KLF4 Peptide - P1211 from Novus Biologicals Category Peptide Species Human

KLF4-Antibody-Center-Blocking-peptide - BP12069c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KLF4-Antibody-C-term-Blocking-peptide - BP11958b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KLF4-Antibody-Blocking-peptide - BP2725f from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KLF4-Antibody-N-term-Blocking-Peptide - BP2725d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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