PKP2

Gene Symbol PKP2
Entrez Gene 5318
Alt Symbol ARVD9
Species Human
Gene Type protein-coding
Description plakophilin 2
Other Description plakophilin-2
Swissprots B8QFA1 B8QGS7 Q99959 B8QGS6 D3DUW9 Q99960 A0AV37 Q4VC01
Accessions ACD03459 EAW88511 EAW88512 EAW88513 EAW88514 EAW88515 EAW88516 Q99959 AK299139 BAG61191 AU125826 AW439621 BC070083 BC094762 AAH94762 BC126199 AAI26200 BC143966 AAI43967 BC143967 BX956935 DB454360 EU520483 ACD13292 EU520484 ACD13293 EU520485 ACD13294 EU520486 ACD13295 HQ258660 ADR83411 X97675 CAA66264 NM_001005242 NP_001005242 NM_004572 NP_004563
Function May play a role in junctional plaques. {ECO:0000269|PubMed:22781308}.
Subcellular Location Nucleus {ECO:0000269|PubMed:22781308}. Cell junction, desmosome {ECO:0000269|PubMed:22781308}. Note=Nuclear and associated with desmosomes.
Tissue Specificity Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata. {ECO:0000269|PubMed:10374264, ECO:0000269|PubMed:22781308}.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Human PKP2 Gene cDNA Clone - orb144756 from Biorbyt

Prices $519.00
Sizes 10 μg
Species Human

PKP2 - MBS1269081 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC126199

human PKP2 ORF clone (NM_001005242.2) - CDCH064372 from Creative biogene

Species Human

Human PKP2 ORF Clone (BC126199) - CDCS406231 from Creative biogene

Species Human
Accession Q99959

Human PKP2 ORF clone (BC126199) - CDCB157936 from Creative biogene

Species Human
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