Gene Symbol | PKP2 |
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Entrez Gene | 5318 |
Alt Symbol | ARVD9 |
Species | Human |
Gene Type | protein-coding |
Description | plakophilin 2 |
Other Description | plakophilin-2 |
Swissprots | B8QFA1 B8QGS7 Q99959 B8QGS6 D3DUW9 Q99960 A0AV37 Q4VC01 |
Accessions | ACD03459 EAW88511 EAW88512 EAW88513 EAW88514 EAW88515 EAW88516 Q99959 AK299139 BAG61191 AU125826 AW439621 BC070083 BC094762 AAH94762 BC126199 AAI26200 BC143966 AAI43967 BC143967 BX956935 DB454360 EU520483 ACD13292 EU520484 ACD13293 EU520485 ACD13294 EU520486 ACD13295 HQ258660 ADR83411 X97675 CAA66264 NM_001005242 NP_001005242 NM_004572 NP_004563 |
Function | May play a role in junctional plaques. {ECO:0000269|PubMed:22781308}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22781308}. Cell junction, desmosome {ECO:0000269|PubMed:22781308}. Note=Nuclear and associated with desmosomes. |
Tissue Specificity | Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata. {ECO:0000269|PubMed:10374264, ECO:0000269|PubMed:22781308}. |
Top Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Human Plakophilin 2 peptide - ab71582 from Abcam
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PKP2 / Plakophilin 2 Antibody Blocking Peptide - LS-E2056 from LifeSpan Bioscience
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PKP2 / Plakophilin 2 Antibody Blocking Peptide - LS-E27654 from LifeSpan Bioscience
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PKP2 / Plakophilin 2 Antibody Blocking Peptide - LS-E20565 from LifeSpan Bioscience
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PKP2-Antibody-C-term-Blocking-peptide - BP12940b from Abgent, a WuXi AppTec company
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Plakophilin 2 Blocking Peptide - 33R-3813 from Fitzgerald
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Plakophilin 2 Peptide - AC21-2471-P from Abcore
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PKP2 Peptide - 42-422P from ProSci
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PKP2 fusion protein - ag12038 from Proteintech Group
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PKP2 fusion protein - Ag12220 from Proteintech Group
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Recombinant Plakophilin 2 (PKP2) - RPA445Hu01 from Uscn Life Science Inc.
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Plakophilin 2 (P663) Peptide - BS3368P from Bioworld Technology
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Recombinant Plakophilin 2 (PKP2) - RPA445Hu01 from Cloud-clone
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Recombinant Human Plakophilin-2(PKP2) ,partial - CSB-YP859116HU CSB-EP859116HU CSB-BP859116HU CSB-MP859116HU from Cusabio
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Plakophilin 2 Protein (Recombinant) - abx167143 from Abbexa
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Plakophilin 2, Recombinant Protein - MBS2029229 from MyBioSource
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Plakophilin-2 (PKP2), partial, Recombinant Protein - MBS1468156 from MyBioSource
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Plakophilin 2, Peptide - MBS427543 from MyBioSource
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Plakophilin 2 Recombinant Protein Antigen - NBP1-86078PEP from Novus Biologicals
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Plakophilin 2 Blocking Peptide - abx061683 from Abbexa
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PKP2 Peptide, Human - M34GP11855H from Creative Peptides
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Plakophilin 2 Blocking Peptide - CBP7073 from Cohesion Biosciences
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Plakophilin 2 peptide - orb339290 from Biorbyt
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PKP2 Immunizing peptide - orb66210 from Biorbyt
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Recombinant Plakophilin 2 (PKP2) - RPU54038 from Biomatik
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