PKP2

Gene Symbol PKP2
Entrez Gene 5318
Alt Symbol ARVD9
Species Human
Gene Type protein-coding
Description plakophilin 2
Other Description plakophilin-2
Swissprots B8QFA1 B8QGS7 Q99959 B8QGS6 D3DUW9 Q99960 A0AV37 Q4VC01
Accessions ACD03459 EAW88511 EAW88512 EAW88513 EAW88514 EAW88515 EAW88516 Q99959 AK299139 BAG61191 AU125826 AW439621 BC070083 BC094762 AAH94762 BC126199 AAI26200 BC143966 AAI43967 BC143967 BX956935 DB454360 EU520483 ACD13292 EU520484 ACD13293 EU520485 ACD13294 EU520486 ACD13295 HQ258660 ADR83411 X97675 CAA66264 NM_001005242 NP_001005242 NM_004572 NP_004563
Function May play a role in junctional plaques. {ECO:0000269|PubMed:22781308}.
Subcellular Location Nucleus {ECO:0000269|PubMed:22781308}. Cell junction, desmosome {ECO:0000269|PubMed:22781308}. Note=Nuclear and associated with desmosomes.
Tissue Specificity Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata. {ECO:0000269|PubMed:10374264, ECO:0000269|PubMed:22781308}.
Top Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)

plakophilin 2 CRISPR/Cas9 KO Plasmid (h) - sc-402990 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 HDR Plasmid (h) - sc-402990-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 Double Nickase Plasmid (h) - sc-402990-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 Double Nickase Plasmid (h2) - sc-402990-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 CRISPR Activation Plasmid (h) - sc-402990-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 CRISPR Activation Plasmid (h2) - sc-402990-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 Lentiviral Activation Particles (h) - sc-402990-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 Lentiviral Activation Particles (h2) - sc-402990-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plakophilin 2 siRNA (h) - sc-43182 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Plakophilin 2 shRNA Plasmid (h) - sc-43182-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Plakophilin 2 shRNA (h) Lentiviral Particles - sc-43182-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU117641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU070891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16877 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16877 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09891 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09891

PKP2 siRNA (Human) - CRH3559 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PKP2(NM_004572.3) - SHR118344 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PKP2(NM_001005242.2) - SHR118380 from Creative biogene

Category siRNA
Species Reactivities Human

Human PKP2 siRNA - orb264061 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PKP2 shRNA Plasmid (Human) - CHH3559 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PKP2 miRNA 3'UTR clone - MiUTR1H-07948 from Creative biogene

Species Reactivities Human

PKP2 miRNA 3'UTR clone - MiUTR1H-07949 from Creative biogene

Species Reactivities Human
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