| Gene Symbol |
ELP5
|
| Entrez Gene |
23587
|
| Alt Symbol |
C17orf81, DERP6, HSPC002, MST071, MSTP071
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
elongator acetyltransferase complex subunit 5
|
| Other Description |
S-phase 2 protein|dermal papilla derived protein 6|elongator complex protein 5
|
| Swissprots |
Q8TDR9 Q7Z2T4 Q9BUB2 Q8TE02 A8K1M5 D3DTN9 Q659B6 Q9Y2Q4
|
| Accessions |
EAW90230 EAW90231 EAW90232 Q8TE02 AB013910 BAB87800 AF070658 AAD20964 AF087868 AAM10496 AF163262 AAQ13591 AK225983 AK289940 BAF82629 AL713741 CAH56280 BC002762 AAH02762 BE743557 BF921423 BF982004 BI916017 BM970924 BP230198 BQ648358 CA431021 CA450318 CF135215 XM_011523779 XP_011522081 NM_015362 NP_056177 NM_203413 NP_981958 NM_203414 NP_981959 NM_203415 NP_981960
|
| Function |
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation. {ECO:0000250, ECO:0000269|PubMed:16850183}.
|
| Subcellular Location |
Nucleus. Cytoplasm.
|
| Tissue Specificity |
Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis.
|