Gene Symbol | ELP5 |
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Entrez Gene | 23587 |
Alt Symbol | C17orf81, DERP6, HSPC002, MST071, MSTP071 |
Species | Human |
Gene Type | protein-coding |
Description | elongator acetyltransferase complex subunit 5 |
Other Description | S-phase 2 protein|dermal papilla derived protein 6|elongator complex protein 5 |
Swissprots | Q8TDR9 Q7Z2T4 Q9BUB2 Q8TE02 A8K1M5 D3DTN9 Q659B6 Q9Y2Q4 |
Accessions | EAW90230 EAW90231 EAW90232 Q8TE02 AB013910 BAB87800 AF070658 AAD20964 AF087868 AAM10496 AF163262 AAQ13591 AK225983 AK289940 BAF82629 AL713741 CAH56280 BC002762 AAH02762 BE743557 BF921423 BF982004 BI916017 BM970924 BP230198 BQ648358 CA431021 CA450318 CF135215 XM_011523779 XP_011522081 NM_015362 NP_056177 NM_203413 NP_981958 NM_203414 NP_981959 NM_203415 NP_981960 |
Function | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation. {ECO:0000250, ECO:0000269|PubMed:16850183}. |
Subcellular Location | Nucleus. Cytoplasm. |
Tissue Specificity | Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis. |
DERP6 (E-4) - sc-514018 from Santa Cruz Biotechnology
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DERP6 (H-113) - sc-382439 from Santa Cruz Biotechnology
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DERP6 (K-18) - sc-103458 from Santa Cruz Biotechnology
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Anti-C17orf81 antibody - ab87175 from Abcam
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Anti-C17orf81 antibody - ab74923 from Abcam
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Anti-ELP5 Antibody (C-Terminus) - LS-C81822 from LifeSpan Bioscience
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Anti-ELP5 Antibody (aa143-192) - LS-C102551 from LifeSpan Bioscience
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DERP6 Antibody - NBP1-85250 from Novus Biologicals
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DERP6 Antibody - NBP1-57696 from Novus Biologicals
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DERP6 Antibody - NBP1-57705 from Novus Biologicals
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DERP6 Polyclonal Antibody - bs-9638R from Bioss
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Anti-C17ORF81 antibody produced in rabbit - AV53845 from Sigma-Aldrich
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Anti-C17ORF81 antibody produced in rabbit - SAB2103461 from Sigma-Aldrich
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Anti-ELP5 antibody produced in rabbit - HPA023279 from Sigma-Aldrich
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C17orf81 antibody - middle region (ARP53704_P050) - ARP53704_P050 from Aviva Systems Biology
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C17orf81 antibody - C-terminal region (ARP53845_P050) - ARP53845_P050 from Aviva Systems Biology
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C17ORF81 antibody, C-term - GTX45445 from GeneTex
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C17ORF81 antibody, Internal - GTX45475 from GeneTex
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C17ORF81 antibody - 70R-3959 from Fitzgerald
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C17ORF81 antibody - 70R-3946 from Fitzgerald
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DERP6 antibody - 10162-1-AP from Acris Antibodies
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DERP6 antibody - H00023587-B01P from Acris Antibodies
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C17orf81 Antibody - 26-823 from ProSci
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C17orf81 Antibody - 30-952 from ProSci
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C17orf81 antibody - 10162-1-AP from Proteintech Group
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