Gene Symbol | ELP5 |
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Entrez Gene | 23587 |
Alt Symbol | C17orf81, DERP6, HSPC002, MST071, MSTP071 |
Species | Human |
Gene Type | protein-coding |
Description | elongator acetyltransferase complex subunit 5 |
Other Description | S-phase 2 protein|dermal papilla derived protein 6|elongator complex protein 5 |
Swissprots | Q8TDR9 Q7Z2T4 Q9BUB2 Q8TE02 A8K1M5 D3DTN9 Q659B6 Q9Y2Q4 |
Accessions | EAW90230 EAW90231 EAW90232 Q8TE02 AB013910 BAB87800 AF070658 AAD20964 AF087868 AAM10496 AF163262 AAQ13591 AK225983 AK289940 BAF82629 AL713741 CAH56280 BC002762 AAH02762 BE743557 BF921423 BF982004 BI916017 BM970924 BP230198 BQ648358 CA431021 CA450318 CF135215 XM_011523779 XP_011522081 NM_015362 NP_056177 NM_203413 NP_981958 NM_203414 NP_981959 NM_203415 NP_981960 |
Function | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation. {ECO:0000250, ECO:0000269|PubMed:16850183}. |
Subcellular Location | Nucleus. Cytoplasm. |
Tissue Specificity | Ubiquitously expressed with high levels in heart, brain, liver, skeletal muscle and testis. |
Human C17orf81 full length protein - ab168089 from Abcam
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ELP5 Antibody Blocking Peptide - LS-E19420 from LifeSpan Bioscience
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ELP5 Antibody Blocking Peptide - LS-E19509 from LifeSpan Bioscience
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Recombinant Human DERP6 Protein - NBP2-23019 from Novus Biologicals
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Human ELP5 protein - orb191287 from Biorbyt
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C17ORF81 Blocking Peptide - 33R-3697 from Fitzgerald
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C17ORF81 Blocking Peptide - 33R-3064 from Fitzgerald
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ELP5 protein (His tag) - 80R-2980 from Fitzgerald
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DERP6 (1-316, His-tag) - AR51098PU-N from Acris Antibodies
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DERP6 (1-316, His-tag) - AR51098PU-S from Acris Antibodies
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ELP5, 1-316aa, Human, His tag, E.coli - 01-P2274 from ARP American Research Products
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C17orf81 fusion protein - Ag0194 from Proteintech Group
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C17orf81 fusion protein - ag0216 from Proteintech Group
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Recombinant Human C17orf81, GST-tagged - C17orf81-10425H from Creative Biomart
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Recombinant Human ELP5, His-tagged - ELP5-15918H from Creative Biomart
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Recombinant Human Dermal papilla-derived protein 6(DERP6) - CSB-YP855062HU CSB-EP855062HU CSB-BP855062HU CSB-MP855062HU from Cusabio
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ELP5, 1-316aa, Human, His tag, E.coli - ATGP2274 from ATGen
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DERP6 Recombinant Protein Antigen - NBP1-85250PEP from Novus Biologicals
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Elongator Acetyltransferase Complex Subunit 5 Protein (Recombinant) - abx262684 from Abbexa
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ELP5 Peptide, Human - M34GP04885H from Creative Peptides
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ELP5 - PAT-82273-1 from Nordic BioSite
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ELP5 - PAT-82273-2 from Nordic BioSite
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Elongator Acetyltransferase Complex Subunit 5, Human Recombinant - 228-21768-1 from RayBiotech
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Dermal papilla-derived protein 6 (DERP6), Recombinant Protein - MBS1454897 from MyBioSource
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Elongator Acetyltransferase Complex, Recombinant Protein - MBS145936 from MyBioSource
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