CLEC16A

Gene Symbol CLEC16A
Entrez Gene 23274
Alt Symbol Gop-1, KIAA0350
Species Human
Gene Type protein-coding
Description C-type lectin domain family 16, member A
Other Description C-type lectin domain family 16 member A|protein CLEC16A
Swissprots Q6ZTB2 O15058 Q2KHT3
Accessions EAW85164 EAW85165 Q2KHT3 AB002348 BAA20807 AK125825 AK126771 AW072095 BC009721 BC112897 AAI12898 BX374760 DB062118 DB069341 XM_005255210 XP_005255267 XM_005255211 XP_005255268 XM_005255213 XP_005255270 XM_005255214 XP_005255271 XM_005255215 XP_005255272 XM_005255216 XP_005255273 XM_006720870 XP_006720933 XM_011522434 XP_011520736 XM_011522435 XP_011520737 XM_011522436 XP_011520738 XM_011522437 XP_011520739 XM_011522438 XP_011520740 XM_011522439 XP_011520741 XM_011522440 XP_011520742 XR_932810 NM_001243403 NP_001230332 NM_015226 NP_056041
Function Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. {ECO:0000269|PubMed:24949970}.
Subcellular Location Endosome membrane {ECO:0000250|UniProtKB:Q80U30}; Peripheral membrane protein. Lysosome membrane {ECO:0000250|UniProtKB:Q80U30}; Peripheral membrane protein. Note=Associates with the endolysosome membrane. {ECO:0000250|UniProtKB:Q80U30}.
Tissue Specificity Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells. {ECO:0000269|PubMed:17632545}.

CLEC16A overexpression lysate - LY414698 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

Panoply™ Human CLEC16A Knockdown Stable Cell Line - CSC-DC003253 from Creative biogene

Category Cell Line
Species Human
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