CLEC16A

Gene Symbol CLEC16A
Entrez Gene 23274
Alt Symbol Gop-1, KIAA0350
Species Human
Gene Type protein-coding
Description C-type lectin domain family 16, member A
Other Description C-type lectin domain family 16 member A|protein CLEC16A
Swissprots Q6ZTB2 O15058 Q2KHT3
Accessions EAW85164 EAW85165 Q2KHT3 AB002348 BAA20807 AK125825 AK126771 AW072095 BC009721 BC112897 AAI12898 BX374760 DB062118 DB069341 XM_005255210 XP_005255267 XM_005255211 XP_005255268 XM_005255213 XP_005255270 XM_005255214 XP_005255271 XM_005255215 XP_005255272 XM_005255216 XP_005255273 XM_006720870 XP_006720933 XM_011522434 XP_011520736 XM_011522435 XP_011520737 XM_011522436 XP_011520738 XM_011522437 XP_011520739 XM_011522438 XP_011520740 XM_011522439 XP_011520741 XM_011522440 XP_011520742 XR_932810 NM_001243403 NP_001230332 NM_015226 NP_056041
Function Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. {ECO:0000269|PubMed:24949970}.
Subcellular Location Endosome membrane {ECO:0000250|UniProtKB:Q80U30}; Peripheral membrane protein. Lysosome membrane {ECO:0000250|UniProtKB:Q80U30}; Peripheral membrane protein. Note=Associates with the endolysosome membrane. {ECO:0000250|UniProtKB:Q80U30}.
Tissue Specificity Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells. {ECO:0000269|PubMed:17632545}.

CLEC-16A CRISPR/Cas9 KO Plasmid (h) - sc-406372 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A HDR Plasmid (h) - sc-406372-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A Double Nickase Plasmid (h) - sc-406372-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A Double Nickase Plasmid (h2) - sc-406372-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A CRISPR Activation Plasmid (h) - sc-406372-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A CRISPR Activation Plasmid (h2) - sc-406372-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A Lentiviral Activation Particles (h) - sc-406372-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A Lentiviral Activation Particles (h2) - sc-406372-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-16A siRNA (h) - sc-93056 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-16A shRNA Plasmid (h) - sc-93056-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-16A shRNA (h) Lentiviral Particles - sc-93056-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU041561 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6201 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6201 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLEC16A siRNA (Human) - CRH8143 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLEC16A - MBS8226847 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLEC16A (NM_015226.2) - SHH264953 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLEC16A siRNA - orb268645 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLEC16A shRNA Plasmid (Human) - CHH8143 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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