IMPACT

Gene Symbol	IMPACT
Entrez Gene	55364
Alt Symbol	RWDD5
Species	Human
Gene Type	protein-coding
Description	impact RWD domain protein
Other Description	Impact homolog|RWD domain containing 5|imprinted and ancient gene protein homolog|protein IMPACT
Swissprots	Q9H2X4 A8MXG0 Q49AM0 Q9P2X3
Accessions	AAG23917 AAS93618 CAV24109 CBF65942 CBU90814 EAX01184 EAX01185 EAX01186 EAX01187 EAX01188 Q9P2X3 AB026264 BAA95160 AF208694 AAG35736 AK292533 BAF85222 AK312727 BC034016 AAH34016 BC036074 AAH36074 BP384088 DQ893141 ABM84067 EU176771 ABW03572 NM_018439 NP_060909
Function	Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Note=May be associated with polysomes. {ECO:0000250}.
Tissue Specificity	Widely expressed. Expressed at high level in brain. {ECO:0000269|PubMed:11116084, ECO:0000269|PubMed:11244491}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IMPACT full length protein - ab163086 from Abcam Category Protein Source Wheat germ Species Human

Human IMPACT full length protein - ab168072 from Abcam Category Protein Source E. coli Species Human

IMPACT Antibody Blocking Peptide - LS-E5129 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IMPACT Recombinant Protein - H00055364-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human IMPACT Protein - NBP2-23135 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

IMPACT-Antibody-N-term-Blocking-Peptide - BP17553a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human IMPACT protein - orb191232 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

IMPACT protein (His tag) - 80R-2972 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

IMPACT (1-320, His-tag) - AR51090PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

IMPACT (1-320, His-tag) - AR51090PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

IMPACT - H00055364-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IMPACT - H00055364-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IMPACT, 1-320aa, Human, His tag, E.coli - 01-P2266 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

IMPACT fusion protein - Ag9890 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

IMPACT fusion protein - Ag9776 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human IMPACT, His-tagged - IMPACT-15910H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human IMPACT, His-tagged - IMPACT-106H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein IMPACT(IMPACT) - CSB-YP889191HU CSB-EP889191HU CSB-BP889191HU CSB-MP889191HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

IMPACT, 1-320aa, Human, His tag, E.coli - ATGP2266 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Impact homolog (mouse) (IMPACT) - TP304631 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

IMPACT Recombinant Protein Antigen - NBP1-86221PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IMPACT Recombinant Protein Antigen - NBP1-86234PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IMPACT Peptide, Human - M34GP07631H from Creative Peptides Category Peptide Source Synthetic. Species Human

IMPACT - PAT-82265-1 from Nordic BioSite Category Protein Species Human

IMPACT - PAT-82265-2 from Nordic BioSite Category Protein Species Human

Search more