KCNJ6

Gene Symbol KCNJ6
Entrez Gene 3763
Alt Symbol BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 6
Other Description G protein-activated inward rectifier potassium channel 2|inward rectifier K(+) channel Kir3.2|inward rectifier potassium channel KIR3.2
Swissprots Q3MJ74 P48051 Q53WW6
Accessions AAB34738 EAX09692 P48051 AJ001894 AK313997 BAG36709 AW015013 BC101547 AAI01548 BF110130 D87327 BAA13331 DR000377 HY332424 U24660 AAC50258 XM_011529558 XP_011527860 XM_011529559 XP_011527861 NM_002240 NP_002231
Function This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
Top Pathways GABAergic synapse, Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment

KIR3.2 (C-20) - sc-16135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIR3.2 (C-20): sc-16135. Immunofluorescence staining of methanol-fixed Sol8 cells showing membrane localization.

KIR3.2 (E-17) - sc-139517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

KIR3.2 (S-18) - sc-139516 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-GIRK2 antibody - ab65096 from Abcam

Prices $379.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-GIRK2 antibody (ab65096) at 1 µg/ml + Human Brain (Substantia Nigra) lysate (35µg protein in RIPA buffer).

Anti-GIRK2 antibody - ab66502 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GIRK2 antibody - Cytoplasmic domain - ab81113 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa374-388) - LS-C92566 from LifeSpan Bioscience

Prices $770.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (C-Terminus) - LS-C144782 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (C-Terminus) - LS-C153451 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, AP) - LS-C215376 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, APC) - LS-C215377 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, Biotin) - LS-C215378 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, FITC) - LS-C215379 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, Azide-free, HRP) - LS-C215380 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa26-55, PE) - LS-C215382 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (aa33-63) - LS-C322396 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 Antibody (C-Terminus) - LS-C345386 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of KCNJ6 Antibody with human MCF7 Whole Cell lysate.

Anti-KCNJ6 / GIRK2 Antibody (aa386-397) - LS-C54913 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of Human Brain (Substantia Nigra) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-KCNJ6 / GIRK2 Antibody (aa26-55) - LS-C165435 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KCNJ6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-KCNJ6 / GIRK2 Antibody (N-Terminus) IHC-plus™ - LS-A8377 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNJ6 / GIRK2 antibody LS-A8377 IHC of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-KCNJ6 / GIRK2 Antibody (N-Terminus) IHC-plus™ - LS-A9571 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNJ6 / GIRK2 antibody LS-A9571 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GIRK2 Antibody - NB100-74575 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: GIRK2 Antibody [NB100-74575] - (1ug/ml) staining of Human Brain (Substantia Nigra) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

GIRK2 Antibody - NBP1-20158 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-GIRK2 Polyclonal Antibody - bs-4214R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ6 / GIRK2 antibody produced in rabbit - SAB2900654 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KCNJ6/GIRK2 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900654</B>: Anti-KCNJ6/GIRK2 antibody IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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