KCNJ6

Gene Symbol	KCNJ6
Entrez Gene	3763
Alt Symbol	BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 6
Other Description	G protein-activated inward rectifier potassium channel 2|inward rectifier K(+) channel Kir3.2|inward rectifier potassium channel KIR3.2
Swissprots	Q3MJ74 P48051 Q53WW6
Accessions	AAB34738 EAX09692 P48051 AJ001894 AK313997 BAG36709 AW015013 BC101547 AAI01548 BF110130 D87327 BAA13331 DR000377 HY332424 U24660 AAC50258 XM_011529558 XP_011527860 XM_011529559 XP_011527861 NM_002240 NP_002231
Function	This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
Top Pathways	GABAergic synapse, Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GIRK2 full length protein - ab132375 from Abcam Category Protein Source Wheat germ Species Human

Mouse GIRK2 peptide - ab31823 from Abcam Category Peptide

KCNJ6 / GIRK2 Antibody Blocking Peptide - LS-E8004 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNJ6 / GIRK2 Antibody Blocking Peptide - LS-E29398 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KCNJ6 / GIRK2 Antibody Blocking Peptide - LS-E26467 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNJ6 / GIRK2 Antibody Blocking Peptide - LS-E29690 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human GIRK2 Protein - H00003763-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

KCNJ6-Antibody-Center-Blocking-peptide - BP5852c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GIRK2 blocking peptide - GTX88962-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

GIRK2 Peptide - AC21-1305-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

KCNJ6 - H00003763-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

KCNJ6 - H00003763-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GIRK2 Peptide - 45-672P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

KCNJ6 fusion protein - Ag16344 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

KCNJ6 fusion protein - ag18072 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human KCNJ6, GST-tagged - KCNJ6-259H from Creative Biomart Category Protein Source E.coli Species Human

KCNJ6 - TP310938 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GIRK2/KCNJ6, Peptide - MBS426120 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

KCNJ6 Peptide, Human - M34GP07972H from Creative Peptides Category Peptide Source Synthetic. Species Human

G protein-activated inward rectifier potassium channel 2 (KCNJ6), Recombinant Protein - MBS963564 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

G protein-activated inward rectifier potassium channel 2 (KCNJ6), Recombinant Protein - MBS7017711 from MyBioSource Category Protein Prices $1,225.00, $2,215.00, $3,420.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human KCNJ6 Protein, MYC/DDK-tagged - KCNJ6-355H from Creative Biomart Category Protein Source HEK293 Species Human

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