KCNJ6

Gene Symbol KCNJ6
Entrez Gene 3763
Alt Symbol BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 6
Other Description G protein-activated inward rectifier potassium channel 2|inward rectifier K(+) channel Kir3.2|inward rectifier potassium channel KIR3.2
Swissprots Q3MJ74 P48051 Q53WW6
Accessions AAB34738 EAX09692 P48051 AJ001894 AK313997 BAG36709 AW015013 BC101547 AAI01548 BF110130 D87327 BAA13331 DR000377 HY332424 U24660 AAC50258 XM_011529558 XP_011527860 XM_011529559 XP_011527861 NM_002240 NP_002231
Function This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
Top Pathways GABAergic synapse, Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment

KIR3.2 CRISPR/Cas9 KO Plasmid (h) - sc-405031 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 HDR Plasmid (h) - sc-405031-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 Double Nickase Plasmid (h) - sc-405031-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 Double Nickase Plasmid (h2) - sc-405031-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 CRISPR Activation Plasmid (h) - sc-405031-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 CRISPR Activation Plasmid (h2) - sc-405031-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 Lentiviral Activation Particles (h) - sc-405031-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 Lentiviral Activation Particles (h2) - sc-405031-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR3.2 siRNA (h) - sc-42618 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIR3.2 shRNA Plasmid (h) - sc-42618-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIR3.2 shRNA (h) Lentiviral Particles - sc-42618-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GIRK2 RNAi - H00003763-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU021101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10959 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10959 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06184 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06184

KCNJ6 siRNA (Human) - CRH2539 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KCNJ6 (NM_002240.3) - SHH323323 from Creative biogene

Category siRNA
Species Reactivities Human

KCNJ6 shRNA Plasmid (Human) - CHH2539 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNJ6 miRNA 3'UTR clone - MiUTR3H-03709 from Creative biogene

Species Reactivities Human
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