DEAF1

Gene Symbol	DEAF1
Entrez Gene	10522
Alt Symbol	MRD24, NUDR, SPN, ZMYND5
Species	Human
Gene Type	protein-coding
Description	DEAF1 transcription factor
Other Description	deformed epidermal autoregulatory factor 1 homolog|nuclear DEAF-1-related transcriptional regulator|suppressin|zinc finger MYND domain-containing protein 5
Swissprots	A8K1F8 C7T5V5 O75398 O75399 O15152 O75512 O75513 O75511 O75510 Q9UET1 A8K5R8
Accessions	EAX02370 EAX02371 O75398 AB209831 BAD93068 AF007165 AAB62704 AF049459 AAC79676 AF049460 AAC79677 AF068892 AAC25714 AF068893 AAC25715 AF068894 AAC25716 AF068895 AAC25717 AF068896 AAC25718 AF068897 AAC25719 AK289873 BAF82562 AK291383 BAF84072 BC042135 BC053322 AAH53322 BI463261 BM696110 BQ267366 EU831436 ACE87123 EU831528 ACE86447 FJ985253 ACU88060 HY094363 HY324291 XM_011519842 XP_011518144 XM_011519843 XP_011518145 XR_428838 XR_930843 NM_001293634 NP_001280563 NM_021008 NP_066288
Function	Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'- AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein- protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3. {ECO:0000269|PubMed:10521432, ECO:0000269|PubMed:11427895, ECO:00
Subcellular Location	Isoform 3: Secreted. Note=Secreted in some cell types.
Tissue Specificity	Expressed in various tissues and cells such as in peripheral mononuclear cells and hormone-secreting pituitary cells. Expression in pancreatic lymph nodes of patients with type 1 diabetes is 20 times higher than in healthy controls. Highly expressed in fetal and adult brain. {ECO:0000269|PubMed:19668219, ECO:0000269|PubMed:24726472}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Deformed Epidermal Autoregulatory Factor 1 full length protein - ab161032 from Abcam Category Protein Source Wheat germ Species Human

Human Deformed Epidermal Autoregulatory Factor 1 protein fragment - ab161033 from Abcam Category Protein Source Wheat germ Species Human

Human Deformed Epidermal Autoregulatory Factor 1 protein fragment - ab161034 from Abcam Category Protein Source Wheat germ Species Human

NUDR / DEAF1 Antibody Blocking Peptide - LS-E4151 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUDR / DEAF1 Antibody Blocking Peptide - LS-E14268 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DEAF1 Protein - H00010522-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DEAF1 Protein - H00010522-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

DEAF1 Partial Recombinant Protein - H00010522-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DEAF1-Antibody-C-term-Blocking-Peptide - BP16405b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DEAF1 - H00010522-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DEAF1 - H00010522-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DEAF1 - H00010522-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DEAF1 - H00010522-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

DEAF1 - H00010522-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DEAF1 - H00010522-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DEAF1 fusion protein - Ag13145 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

DEAF1 fusion protein - Ag13173 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human DEAF1, His-tagged - DEAF1-11919H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Deformed epidermal autoregulatory factor 1 homolog(DEAF1) - CSB-YP006644HU CSB-EP006644HU CSB-BP006644HU CSB-MP006644HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Human Deformed Epidermal Autoregulatory Factor 1 full length protein - ab204219 from Abcam Category Protein Source E. coli Species Human

DEAF1 Protein - NBP2-47489PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

DEAF1 Peptide, Human - M34GP04173H from Creative Peptides Category Peptide Source Synthetic. Species Human

Deformed epidermal autoregulatory factor 1 homolog (DEAF1), Recombinant Protein - MBS1089642 from MyBioSource Category Protein Prices $1,360.00, $1,360.00, $1,580.00, $1,580.00, $2,265.00, $2,265.00, $2,730.00, $2,730.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more