BCO2

Gene Symbol BCO2
Entrez Gene 83875
Alt Symbol B-DIOX-II, BCDO2
Species Human
Gene Type protein-coding
Description beta-carotene oxygenase 2
Other Description b,b-carotene-9',10'-dioxygenase|beta,beta-carotene 9',10'-dioxygenase variant 1|beta,beta-carotene 9',10'-oxygenase|beta-carotene 9',10' oxygenase|beta-carotene dioxygenase 2|carotenoid-9',10'-cleaving dioxygenase
Swissprots B4DNC3 E9PBI8 Q96JY5 Q8IUS0 E9PJJ1 Q96JC8 Q9BYV7 B0YIX5
Accessions ACA05952 EAW67189 EAW67190 EAW67191 EAW67192 EAW67193 EAW67194 Q9BYV7 AB096252 AF276432 AAK69433 AJ290393 CAC27994 AK027801 BAB55379 AK091783 BAC03747 AK297853 BAG60185 AK315300 BAG37705 BC041656 AAH41656 BC047934 BU732625 BX503569 CB162567 CD708042 NM_001037290 NP_001032367 NM_001256397 NP_001243326 NM_001256398 NP_001243327 NM_001256400 NP_001243329 NM_031938 NP_114144
Function Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects. {ECO:0000269|PubMed:21106934}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:21106934}.
Tissue Specificity Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level). {ECO:0000269|PubMed:15983114}.

Human BCO2 / BCDO2 ELISA Kit (Sandwich ELISA) - LS-F10918 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.78
Range 0.78-50 ng/ml

Beta,beta-carotene 9',10'-oxygenase, BCO2, Human, ELISA Kit - E10866h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.78-50 ng/mL

beta, beta-carotene 9', 10'-oxygenase, BCO2, ELISA Kit - MBS9306633 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse BCO2 / BCDO2 ELISA Kit (Custom ELISA) - LS-F15957 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.78-50 ng/ml

Beta,beta-carotene 9',10'-oxygenase, ELISA Kit - MBS288104 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Beta,beta-carotene 9',10'-oxygenase ELISA Kit - abx250481 from Abbexa

Category ELISA Kit
Range 0.78 ng/ml - 50 ng/ml

Human Beta,beta-carotene 9',10'-oxygenase ELISA Kit - EKE52714 from Biomatik

Category ELISA Kit
Prices $685.40, $2,912.95, $5,483.20
Sizes 96 t, 5x96t, 10x96t
Sensitivity The minimum detectable dose of this kit is typically less than 0.23 ng/mL
Range 0.78-50 ng/mL

BCO2 - EKH2448 from Nordic BioSite

Sensitivity 0.469ng/ml
Range 0.78-50ng/ml

BCO2 ELISA Kit (Human) (OKEH02120) - OKEH02120 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 0.23 ng/mL
Range 0.78 - 50 ng/mL

Human BCO2 ELISA Kit - E004721 from Biobool

Category ELISA Kit

Human Beta,beta-carotene 9',10'-oxygenase ELISA Kit - EK2713 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Sensitivity less than 0.23ng/mL
Range 0.78-50 ng/mL

Beta, beta-carotene 9', 10'-oxygenase, ELISA Kit - MBS9426550 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Sensitivity Less than 0.23ng/mL
Range 0.78-50 ng/mL

Beta,beta-carotene 9',10'-oxygenase, ELISA Kit - MBS765460 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.469ng/ml
Range 0.78-50ng/ml

Beta,beta-carotene 9',10'-oxygenase, ELISA Kit - MBS2886831 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.78-50 ng/mL

Human BCO2 / BCDO2 ELISA Kit (Sandwich ELISA) - LS-F34182 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.469
Range 0.78-50 ng/ml
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