BCO2

Gene Symbol	BCO2
Entrez Gene	83875
Alt Symbol	B-DIOX-II, BCDO2
Species	Human
Gene Type	protein-coding
Description	beta-carotene oxygenase 2
Other Description	b,b-carotene-9',10'-dioxygenase|beta,beta-carotene 9',10'-dioxygenase variant 1|beta,beta-carotene 9',10'-oxygenase|beta-carotene 9',10' oxygenase|beta-carotene dioxygenase 2|carotenoid-9',10'-cleaving dioxygenase
Swissprots	B4DNC3 E9PBI8 Q96JY5 Q8IUS0 E9PJJ1 Q96JC8 Q9BYV7 B0YIX5
Accessions	ACA05952 EAW67189 EAW67190 EAW67191 EAW67192 EAW67193 EAW67194 Q9BYV7 AB096252 AF276432 AAK69433 AJ290393 CAC27994 AK027801 BAB55379 AK091783 BAC03747 AK297853 BAG60185 AK315300 BAG37705 BC041656 AAH41656 BC047934 BU732625 BX503569 CB162567 CD708042 NM_001037290 NP_001032367 NM_001256397 NP_001243326 NM_001256398 NP_001243327 NM_001256400 NP_001243329 NM_031938 NP_114144
Function	Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects. {ECO:0000269|PubMed:21106934}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:21106934}.
Tissue Specificity	Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level). {ECO:0000269|PubMed:15983114}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BCO2 / BCDO2 Antibody Blocking Peptide - LS-E701 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCO2 / BCDO2 Antibody Blocking Peptide - LS-E22171 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCO2 / BCDO2 Antibody Blocking Peptide - LS-E22170 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCDO2-Antibody-N-term-Blocking-peptide - BP11050a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BCO2 Blocking Peptide - 33R-2086 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BCO2 fusion protein - ag5946 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

BCO2 fusion protein - Ag5590 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human BCO2 - BCO2-1073H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Beta,beta-carotene 9',10'-oxygenase(BCO2) - CSB-YP874848HU CSB-EP874848HU CSB-BP874848HU CSB-MP874848HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BCO2 Recombinant Protein Antigen - NBP1-90770PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BCO2 Recombinant Protein Antigen - NBP1-90769PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BCO2 Peptide, Human - M34GP01391H from Creative Peptides Category Peptide Source Synthetic. Species Human

Beta,beta-carotene 9',10'-oxygenase (BCO2), Recombinant Protein - MBS1283566 from MyBioSource Category Protein Prices $1,380.00, $1,380.00, $1,595.00, $1,595.00, $2,295.00, $2,295.00, $2,760.00, $2,760.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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