UGGT1

Gene Symbol UGGT1
Entrez Gene 56886
Alt Symbol HUGT1, UGCGL1, UGT1
Species Human
Gene Type protein-coding
Description UDP-glucose glycoprotein glucosyltransferase 1
Other Description UDP--Glc:glycoprotein glucosyltransferase|UDP-glucose ceramide glucosyltransferase-like 1|UDP-glucose:glycoprotein glucosyltransferase 1
Swissprots Q9H8I4 Q53SL3 Q8IW30 Q53QP2 Q9NYU2
Accessions AAY14735 AAY14885 EAW95356 Q9NYU2 AF227905 AAF66232 AK023240 AK023671 BAB14632 AK074251 AK074376 AK293066 BAF85755 AK309101 BC041098 AAH41098 BC047727 BP356698 DB226703 XM_006712634 XP_006712697 XM_006712635 XP_006712698 XM_006712636 XP_006712699 XR_922969 NM_001025777 NM_020120 NP_064505 NR_027671
Function Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. {ECO:0000269|PubMed:10694380}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:10694380}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:10694380}.
Tissue Specificity Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart. {ECO:0000269|PubMed:10694380}.
Top Pathways Protein processing in endoplasmic reticulum

UGGT1 (H-9) - sc-374565 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UGGT1 (H-9): sc-374565. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

UGGT1 (K-16) - sc-47561 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UGGT1 (N-15) - sc-47562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UGGT1 (N-15): sc-47562. Western blot analysis of UGGT1 expression in MCF7 (A) and Jurkat (B) whole cell lysates.

Anti-UGGT antibody - ab129393 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UGGT antibody (ab129393) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-UGGT antibody - ab105704 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-UGGT antibody (ab105704) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-UGGT antibody [EPR5105] - ab124879 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5105
All lanes : Anti-UGGT antibody [EPR5105] (ab124879) at 1/10000 dilutionLane 1 : Human skeletal muscle lysateLane 2 : BXPC-3 cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : MCF7 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-UGGT1 / UGGT Antibody (aa1226-1254, APC) - LS-C242428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1226-1254, AP) - LS-C242427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1226-1254, Biotin) - LS-C242429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1226-1254, FITC) - LS-C242430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1226-1254, Azide-free, HRP) - LS-C247191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1226-1254, PE) - LS-C242431 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (aa1225-1254) - LS-C326167 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UGGT1 / UGGT Antibody (C-Terminus) - LS-C116375 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UGGT1 / UGCGL1 antibody LS-C116375 Western blot of HepG2 cell lysate.

Anti-UGGT1 / UGGT Antibody (Internal, clone EPR5105) - LS-C138319 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5105
IHC of paraffin-embedded human brain tissue using anti-UGGT1 antibody.

Anti-UGGT1 / UGGT Antibody (aa1226-1254) - LS-C160415 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UGCGL1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

UGGT1 Antibody - NBP1-81652 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UGGT1 Antibody [NBP1-81652] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).

UGGT1 Antibody - NBP1-81651 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UGGT1 Antibody - NBP1-70764 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UGGT1 Antibody [NBP1-70764] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

Anti-UGGT1 (human) antibody produced in rabbit - SAB4200374 from Sigma-Aldrich

Prices $343.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Whole extract of HEK-293T cells was separated on SDS-PAGE and probed with Rabbit Anti-UGGT (human) (<B>Cat. No. SAB4200374</B>). The antibody was developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. 1 μg/mL antibody<BR/>2. 2 μg/mL antibody<BR/>3. 2 μg/mL antibody + UGGT immunizing peptide

Anti-UGCGL1 antibody produced in rabbit - SAB2105730 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UGCGL1: <B>Cat. No. SAB2105730</B>: UGCGL1 in HepG2 cell lysates with UGCGL1 antibody at 1.0 μg/mL.

Anti-UGGT1 antibody produced in rabbit - HPA015127 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UGGT1: <B>Cat. No. HPA015127</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-UGGT1 antibody produced in rabbit - HPA012761 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UGGT1: <B>Cat. No. HPA012761</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

UGCGL1 antibody - middle region (ARP49467_P050) - ARP49467_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UGCGL1-Antibody-C-term - AP13145b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
UGCGL1 Antibody (C-term) (Cat. #AP13145b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the UGCGL1 antibody detected the UGCGL1 protein (arrow).
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