DBI

Gene Symbol	DBI
Entrez Gene	1622
Alt Symbol	ACBD1, ACBP, CCK-RP, EP
Species	Human
Gene Type	protein-coding
Description	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Other Description	GABA receptor modulator|acyl coenzyme A binding protein|acyl-CoA-binding protein|acyl-Coenzyme A binding domain containing 1|cholecystokinin-releasing peptide, trypsin-sensitive|diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)|diazepam-binding inhibitor|endozepine
Swissprots	B8ZWD2 P07108 Q6IB48 B8ZWD6 B8ZWD7 Q9UCI8 P08869 Q53SQ7 Q4VWZ6
Accessions	AAY14873 EAW95214 EAW95215 EAW95216 P07108 AA096224 AM000001 CAJ00736 BC006466 BC062996 AAH62996 BM768076 BP294452 BP318721 BU599304 CR456956 CAG33237 DA226476 FM213122 CAR82404 FM213123 CAR82405 FM213124 CAR82406 FM213125 CAR82407 FM213126 CAR82408 FM213127 CAR82409 FM213128 CAR82410 FM213129 CAR82411 FM213130 CAR82412 FM213131 CAR82414 HQ448654 ADQ33132 M14200 AAA52171 M15887 AAA35788 NM_001079862 NP_001073331 NM_001079863 NP_001073332 NM_001178017 NP_001171488 NM_001178041 NP_001171512 NM_001178042 NP_001171513 NM_001178043 NP_001171514 NM_001282633 NP_001269562 NM_001282634 NP_001269563 NM_001282635 NP_001269564 NM_001282636 NP_001269565 NM_020548 NP_065438 NR_104221
Function	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Subcellular Location	Endoplasmic reticulum. Golgi apparatus. Note=Golgi localization is dependent on ligand binding.
Tissue Specificity	Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. {ECO:0000269|PubMed:16055366, ECO:0000269|PubMed:21698759}.
Top Pathways	PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse EP / DBI EIA Kit - LS-F6907 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.3 ng/ml Range 1.11 - 90 ng/ml

Human DBI / ACBD1 ELISA Kit (Sandwich ELISA) - LS-F9926 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.135 ng/ml Range 0.156-10 ng/ml

Mouse DBI / ACBD1 ELISA Kit (Sandwich ELISA) - LS-F9925 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 0.156-10 ng/ml

DBI ELISA kit - 55R-1872 from Fitzgerald Category ELISA Kit Prices $495.00 Sizes 1 kit

Human DBI ELISA Kit - abx151258 from Abbexa Category ELISA Kit Sensitivity 215.6 pmol/L Range 493.83 pmol/L - 40000 pmol/L

Human DBI ELISA Kit - abx151259 from Abbexa Category ELISA Kit Sensitivity 0.106 ng/ml Range 0.313 ng/ml - 20 ng/ml

Acyl-CoA-binding protein (DBI), Human, ELISA Kit - E01A1824 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Carboxypeptidase N subunit 2 (CPN2), Human, ELISA Kit - CSB-EL005899HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Diazepam Binding Inhibitor (DBI), Human, ELISA Kit - CED696Hu from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t Sensitivity 215.6pmol/L Range 493.8-40,000pmol/L

Erythropoietin (EPO), Human, ELISA Kit - SEA028Hu from ARP American Research Products Category ELISA Kit Prices $580.00 Sizes 96 t Sensitivity 2.36pg/mL Range 6.25-400pg/mL

Erythropoietin, EPO, Human, ELISA Kit - CSB-E04538h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.6 mIU/ml Range 3.1 mIU/ml-100 mIU/ml

Erythropoietin (EPO), Human, CLIA Kit - SCA028Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 12.3pg/mL Range 31.2-2,000pg/mL

DBI (Human) ELISA kit - KA0532 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human EP ELISA Kit - HE0174 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine EP ELISA Kit - AE0174 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Acyl CoA binding protein (DBI), ELISA Kit - MBS7201367 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7229216 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7236911 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7201360 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7240790 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7215968 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7231840 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DBI (Human) ELISA Kit - DEIA3315 from Creative Diagnostics Category ELISA Kit Sensitivity The minimal detectable dose of human DBI was calculated to be 25pg/mL.

Human DBI ELISA Kit - DEIA9727 from Creative Diagnostics Category ELISA Kit Sensitivity 25pg/mL

Acyl-CoA-binding protein (DBI), ELISA Kit - MBS7226210 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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